Anamorelin
Anamorelin Basic information
- Product Name:
- Anamorelin
- Synonyms:
-
- anamorelin
- (3R)-1-(2-Methylalanyl-D-tryptophyl)-3-(phenylmethyl)-3-piperidinecarboxylic acid 1,2,2-trimethylhydrazide
- 3-Piperidinecarboxylic acid, 1-(2-methylalanyl-D-tryptophyl)-3-(phenylmethyl)-, trimethylhydrazide, (3R)-
- Rc 1291
- Unii-dd5rba1nkf
- ONO-7643
- Anamorelin (RC-1291)
- (R)-1-((S)-2-((1H-indol-3-yl)methyl)-5-amino-5-methyl-4-oxohexanoyl)-3-benzyl-N,N',N'-trimethylpiperidine-3-carbohydrazide
- CAS:
- 249921-19-5
- MF:
- C31H42N6O3
- MW:
- 546.7
- Mol File:
- 249921-19-5.mol
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Anamorelin Chemical Properties
- Melting point:
- 132-134°C
- Density
- 1.214
- storage temp.
- Refrigerator
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 16.22±0.46(Predicted)
- color
- White to Off-White
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Anamorelin Usage And Synthesis
Uses
Anamorelin functions as a novel therapeutic options for cachexia and sarcopenia. Cancer cachexia and clinical therapeutic interventions.
Biological Activity
Anamorelin is a non-peptidic ghrelin mimetic and growth hormone (GH) secretagogue. It is an orally-active, brain-penetrant, selective agonist of the ghrelin/growth hormone secretagogue receptor (GHSR). Anamorelin has been shown to increases appetite, overall body weight, lean body mass, and muscle strength in clinical studies with cancer patients suffering from cachexia.
AnamorelinSupplier
Shanghai Boyle Chemical Co., Ltd.
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- sales@boylechem.com
Chembest Research Laboratories Limited
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- +86-21-20908456
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Shanghai Kuanghao Chemistry Technology Co., Ltd.
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- 1590082856 15900820856
- 83219210@qq.com
Synches Co., Ltd.
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- 021-53292253
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BOC Sciences
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- 1-631-485-4226; 16314854226
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