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ChemicalBook >  Product Catalog >  Biochemical Engineering >  Amino Acids and Derivatives >  Proline derivatives >  (S)-4-METHYLENE-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER

(S)-4-METHYLENE-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER

Basic information Safety Supplier Related

(S)-4-METHYLENE-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER Basic information

Product Name:
(S)-4-METHYLENE-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER
Synonyms:
  • 1,2-Pyrrolidinedicarboxylicacid, 4-Methylene-, 1-(1,1-diMethylethyl) ester, (2S)-
  • (S)-1-(tert-butoxycarbonyl)-4-Methylenepyrrolidine-2-carboxylic acid
  • N-tert-Butoxycarbonyl-4-methylene-L-proline
  • N-Boc-4-methylene-L-proline 97%
  • N-T-BOC-4-METHYLENE-L-PROLINE
  • (S)-4-METHYLENE-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER
  • BOC-4-METHYLENE-L-PROLINE
  • N-Boc-4-methylene-L-proline
CAS:
84348-38-9
MF:
C11H17NO4
MW:
227.26
Product Categories:
  • pharmacetical
  • Heterocycles
Mol File:
84348-38-9.mol
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(S)-4-METHYLENE-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER Chemical Properties

Melting point:
110-115 °C
Boiling point:
349.9±42.0 °C(Predicted)
Density 
1.18±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. 
2-8°C(protect from light)
pka
3.80±0.20(Predicted)
optical activity
[α]22/D 58°, c = 0.5 in chloroform
Water Solubility 
Insoluble in water.
CAS DataBase Reference
84348-38-9
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26
WGK Germany 
3
HS Code 
2933998090
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(S)-4-METHYLENE-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER Usage And Synthesis

Uses

As important intermediates in various areas such as peptide synthesis, asymmetric synthesis, medicinal chemistry, and polymer chemistry. The fluorous prolins were synthesized from commercially available N-Boc-4-methylene- L-proline.

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