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5-Nitrothiophene-2-carboxylic acid

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5-Nitrothiophene-2-carboxylic acid Basic information

Product Name:
5-Nitrothiophene-2-carboxylic acid
Synonyms:
  • RARECHEM AL BO 0544
  • 5-Nitro-2-thenoic acid
  • 5-NITRO-2-THIOPHENECARBOXYLIC ACID
  • 5-NITROTHIOPHENE-2-CARBOXYLIC ACID
  • BUTTPARK 121\04-13
  • 5-Nitro-2-ThiphenecarboxylicAcid
  • 5-nitro-2-thiophenecarboxylic
  • 2-Carboxy-5-nitrothiophene
CAS:
6317-37-9
MF:
C5H3NO4S
MW:
173.15
EINECS:
228-654-4
Product Categories:
  • Carboxylic Acids
  • Thiophenes & Benzothiophenes
  • Carboxylic Acids
  • Building Blocks
  • Heterocyclic Building Blocks
  • Thiophenes
  • Heterocycles
  • Thiophenes & Benzothiophenes
  • Thiophene&Benzothiophene
Mol File:
6317-37-9.mol
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5-Nitrothiophene-2-carboxylic acid Chemical Properties

Melting point:
154-159℃
Boiling point:
367.2±27.0 °C(Predicted)
Density 
1.676±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
pka
2.69±0.10(Predicted)
form 
Solid
color 
Pale yellow
InChIKey
UNEPVPOHGXLUIR-UHFFFAOYSA-N
CAS DataBase Reference
6317-37-9(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Safety Statements 
24/25
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
29349990

MSDS

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5-Nitrothiophene-2-carboxylic acid Usage And Synthesis

Chemical Properties

Solid

Uses

5-Nitrothiophene-2-carboxylic Acid is a reagent used in the preparation of benzothiophene amides which fuctions as nicotinamide ribosyltransferase inhibitors with potential antitumor and anticancer activities. It also functions as an intermediate in varying organic transformations.

Synthesis Reference(s)

Canadian Journal of Chemistry, 44, p. 2881, 1966 DOI: 10.1139/v66-428
Journal of Medicinal Chemistry, 34, p. 2112, 1991

5-Nitrothiophene-2-carboxylic acid Preparation Products And Raw materials

Raw materials

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