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(-)-GUAIOL

Basic information Aroma Safety Supplier Related

(-)-GUAIOL Basic information

Product Name:
(-)-GUAIOL
Synonyms:
  • 5-Azulenemethanol, 1,2,3,4,5,6,7,8-octahydro-alpha,alpha,3,8-tetramethyl-, [3S-(3alpha,5alpha,8alpha)]-
  • Champaca camphor
  • Champacol
  • Guai-1(5)-en-11-ol
  • Guaiac alcohol
  • Gualol
  • L-rel-Guai-1(5)-en-11-ol
  • 2-((3S,8S)-1,2,3,4,5,6,7,8-octahydro-3,8-dimethylazulen-5-yl)propan-2-ol
CAS:
489-86-1
MF:
C15H26O
MW:
222.37
EINECS:
207-702-8
Mol File:
489-86-1.mol
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(-)-GUAIOL Chemical Properties

Melting point:
91-93 °C(lit.)
Boiling point:
132-136℃
alpha 
D20 -30° (c = 4 in alc)
Density 
0.9714 g/cm3 (20℃)
refractive index 
1.5100 (589.3 nm 20℃)
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Dichloromethane (Sparingly), Ethanol (Slightly), Methanol
form 
Solid
pka
15.11±0.29(Predicted)
color 
White to Off-White
Odor
at 100.00 %. mild guaiacwood tea rose
Odor Type
woody
optical activity
[α]20/D 28°, c = 4 in ethanol
Merck 
13,4572
BRN 
2047993
LogP
4.782 (est)
EPA Substance Registry System
5-Azulenemethanol, 1,2,3,4,5,6,7,8-octahydro-.alpha.,.alpha.,3,8-tetramethyl-, (3S,5R,8S)- (489-86-1)
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Safety Information

Safety Statements 
22-24/25
WGK Germany 
3

MSDS

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(-)-GUAIOL Usage And Synthesis

Aroma

Deteriorates when exposed to air, becomes semi-liquid, darkens in color and changes odor. Mild, rather sweet and very tenacious balsamic-woody odor with an almost floral undertone and a pepperiness which seem to be apparent only in impure material (possibly traces of hydrocarbons).

Chemical Properties

Crystalline solid. Insoluble in water; soluble in alcohol.

Uses

Guaiol is a component of guaiac wood oil, terpenol also found in cannabis.

Definition

A bicyclic sesquiterpene alcohol found in guaiac wood oil.

Production Methods

(-)-Guaiol can be produced by extraction from Guaiacwood oil with a volatile solvent, usually Acetone, Ethanol or Ethylether.
It can also be isolated from the wood of certain Australian members of the family Taxodiaceae, particularly the so-called "Murray River Pine".

General Description

(-)-Guaiol is a sesquiterpene alcohol which has guaiane skeleton. It naturally occurs in essential oils extracted from Salvia lanigera and Helitta ongifoliata and has antibacterial activity.

(-)-GUAIOLSupplier

Meryer (Shanghai) Chemical Technology Co., Ltd.
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tauto@tautobiotech.com