Dibenzyl disulfide Chemical Properties

Melting point:

69-72 °C (lit.)

Boiling point:

210-216°C 18mm

Density 

1.3

refractive index 

1.6210 (estimate)

FEMA 

3617 | BENZYL DISULFIDE

Flash point:

150°C

storage temp. 

2-8°C

solubility 

Chloroform (Slightly), Ethyl Acetate (Slightly)

form 

Solid

color 

White

Odor

at 0.10 % in propylene glycol. smoky burnt earthy green caramel

Odor Type

smoky

JECFA Number

579

Merck 

14,3013

BRN 

1110443

LogP

5.29

CAS DataBase Reference

150-60-7(CAS DataBase Reference)

NIST Chemistry Reference

Benzyl disulfide(150-60-7)

EPA Substance Registry System

Disulfide, bis(phenylmethyl) (150-60-7)

Safety Information

Hazard Codes 

Xi

Risk Statements 

43

Safety Statements 

22-36/37-37-24

WGK Germany 

2

RTECS 

JO1750000

TSCA 

Yes

HS Code 

29309090

MSDS

• Language:English Provider:Benzyl disulfide
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

Dibenzyl disulfide Usage And Synthesis

Chemical Properties

Benzyl disulfide is a pale yellow leafy or small leafy crystals that has a powerful, burnt-caramel odor; irritating when concentrated. Boiling point >270°C(decomposition). Several insoluble in water, soluble in hot ethanol and ether.

Uses

Dibenzyl disulfide has been used in lubricating oil formulations to improve thermal and aging resistance of the oil. It is used an antioxidant in rubber compounding, stabilizer for petroleum fractions, additive to silicone oils. The soly in oils is increased by the presence of benzyl alcohol.

Preparation

Dibenzyl disulfide is synthesized from benzyl chloride and Na2S2; also from benzyl mercaptan via oxidation.
Md. Tajbakhsh et al. (2004) synthesized disulfide from thiols by oxidation with 2,6- DCPCC in acetonitirle at room temperature. For synthesis of DBDS, they used benzyl mercaptan. In 8 min, 96% yield was obtained.

Vivek Polshettiwar et al. (2003) obtained disulfide from reaction of alkyl halide with reagent (C6H5CH2N(Et)3)6Mo7S24 in presence of CHCl3 at room temperature. Pure disulfide was obtained by purification by column chromatography method on silica gel. 89% yield was obtained.

Application

Dibenzyl Disulfide (DBDS) is one of several sulfur compounds known to cause copper corrosion in transformers under certain circumstances. Originating from Petiveria alliacea L. This compound along with the other sulfur-containing compound found in this plant display antibacterial and antifungal activity.

Definition

ChEBI: Dibenzyl disulfide is an organic disulfide that results from the formal oxidative dimerisation of benzyl thiol. It has a role as a metabolite. It is an organic disulfide and an organic aromatic compound.

Synthesis Reference(s)

The Journal of Organic Chemistry, 54, p. 2998, 1989 DOI: 10.1021/jo00274a002
Synthetic Communications, 22, p. 3277, 1992 DOI: 10.1080/00397919208021143
Tetrahedron Letters, 31, p. 5007, 1990 DOI: 10.1016/S0040-4039(00)97790-6

General Description

Dibenzyl Disulfide (DBDS) also called Benzyl disulfide is an aromatic disulfide with molecular formula C14H14S2. It has a structural unit, which consists of a linked pair of sulfur atoms. It is insoluble in water whereas soluble in hot methanol, benzene, ether and hot ethanol. Large disulfides-linked agglomerates are rifely found in proteins and many other biologically active molecules.

Solubility in organics

Poorly soluble in cold alcohol, soluble in hot alcohol and in oils.

Purification Methods

Crystallise the disulfide from EtOH (m 77o), pet ether or CS2 (m 72o) or distil it. The AgNO3 complex has m 103o. [Beilstein 6 H 465, 6 I 229, 6 II 437, 6 III 1635, 6 IV 2760.]

Dibenzyl disulfide(150-60-7)Related Product Information

• Diallyldisulfide
• Dimethylbenzylcarbinyl acetate
• Benzyl isocyanate
• Benzyl benzoate
• Benzyl nicotinate
• DIBENZYLTOLUENE
• Dimethyl disulfide
• Diphenyl ether
• Selenium sulfide
• Thiamine disulfide
• Benzyl chloride
• Benzyl alcohol
• Benzyl
• BENZOYL DISULFIDE
• Zinc dibenzyldithiocarbamate
• DIBENZYLDITHIOCARBAMIC ACID SODIUM SALT
• N,N'-DIBENZYL DITHIOOXAMIDE
• GGKPDLRPCHPPCHYIPRPKPR