8Z,11Z,14Z,17Z-EICOSATETRAENOIC ACID Chemical Properties

Flash point:

14 °C

storage temp. 

−20°C

solubility 

0.1 M Na2CO3: 1.7 mg/ml; DMF: >100 mg/ml; DMSO: >100 mg/ml; Ethanol: Miscible

form 

Colourless Solution

Stability:

Light Sensitive

Safety Information

Hazard Codes 

F

Risk Statements 

11

Safety Statements 

7-16

RIDADR 

UN 1170 3/PG 2

8Z,11Z,14Z,17Z-EICOSATETRAENOIC ACID Usage And Synthesis

Description

ω-3 Arachidonic acid is a rare PUFA found in trace amounts in dietary sources. ω-3 Fatty acids are now known to be essential for infant growth and development and protect against heart disease, thrombosis, hypertension, and inflammatory and autoimmune disorders. In human platelet membranes, ω-3 arachidonic acid inhibits arachidonoyl-CoA synthetase with a K_i of 14 μM. It also inhibits arachidonoyl-CoA synthetase in calf brain extracts with an IC₅₀ value of about 5 μM.

Uses

(all-cis)-8,11,14,17-Eicosatetraenoic Acid (ω-3 Arachidonic acid) is a rare PUFA found in trace amounts in dietary sources. ω-3 Fatty acids are known to be essential for infant development and protect against heart disease, hypertension, thrombosis, and autoimmune and inflammatory disorder. In human platelet membranes, ω-3 Arachidonic acid inhibits arachidonoyl-CoA synthetase.

Definition

ChEBI: All-cis-8,11,14,17-icosatetraenoic acid is an icosatetraenoic acid having four cis double bonds at positions 8, 11, 14 and 17. It has a role as a fungal metabolite. It is an icosatetraenoic acid and an omega-3 fatty acid. It is a conjugate acid of an all-cis-8,11,14,17-icosatetraenoate.

8Z,11Z,14Z,17Z-EICOSATETRAENOIC ACID(24880-40-8)Related Product Information

• ω-3 Arachidonic Acid ethyl ester
• Methyl arachidonoate (8c,11c,14c,17c)
• Arachidonic acid
• (+/-)-8-Hydroxy-5Z,9E,11Z,14Z,17Z-eicosatetraenoic acid
• (+/-)-9-Hydroxy-5Z,7E,11Z,14Z,17Z-eicosatetraenoic acid
• 8Z,11Z,14Z,17Z-EICOSATETRAENOIC-8,9,11,12,14,15,17,18-D8 ACID
• 8Z,11Z,14Z,17Z-EICOSATETRAENOIC ACID
• 8(Z),11(Z),14(Z),17(Z),20(Z)-TRICOSAPENTAENOIC ACID
• 8(Z),11(Z),14(Z),17(Z),20(Z)-TRICOSAPENTAENOIC ACID METHYL ESTER
• (+/-)5(6)-EPOXY-8Z,11Z,14Z,17Z-EICOSATETRAENOIC ACID, METHYL ESTER
• 8Z,11Z,14Z,17Z-EICOSATETRAENOIC ACID, METHYL ESTER