Basic information Safety Supplier Related

Cariprazine

Basic information Safety Supplier Related

Cariprazine Basic information

Product Name:
Cariprazine
Synonyms:
  • Urea, N'-[trans-4-[2-[4-(2,3-dichlorophenyl)-1-piperazinyl]ethyl]cyclohexyl]-N,N -diMethyl-
  • Cariprazine
  • RGH 188;RGH188;RGH-188
  • RGH 188;CARIPRAZINE;RGH188;RGH-188
  • 3-[4-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]cyclohexyl]-1,1-dimethylurea
  • N'-[trans-4-[2-[4-(2,3-Dichlorophenyl)-1-piperazinyl]ethyl]cyclohexyl]-N,N-dimethylurea
  • RGH 188
  • Cariprazine Cas No 839712-12-8 Qty1 gm
CAS:
839712-12-8
MF:
C21H32Cl2N4O
MW:
427.41
EINECS:
1592732-453-0
Product Categories:
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Neurochemicals
  • Pharmaceuticals
  • Inhibitor
  • CARIPRAZINE and Impurities
  • API
Mol File:
839712-12-8.mol
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Cariprazine Chemical Properties

Melting point:
>180°C (dec.)
Density 
1.24
storage temp. 
-20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
Off-White to Light Beige
InChI
InChI=1S/C21H32Cl2N4O/c1-25(2)21(28)24-17-8-6-16(7-9-17)10-11-26-12-14-27(15-13-26)19-5-3-4-18(22)20(19)23/h3-5,16-17H,6-15H2,1-2H3,(H,24,28)/t16-,17-
InChIKey
KPWSJANDNDDRMB-QAQDUYKDSA-N
SMILES
N(C)(C)C(N[C@@H]1CC[C@@H](CCN2CCN(C3=CC=CC(Cl)=C3Cl)CC2)CC1)=O
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Safety Information

Hazardous Substances Data
839712-12-8(Hazardous Substances Data)
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Cariprazine Usage And Synthesis

Uses

Cariprazine is an orally active D2/D3 dopamine receptor antagonist. Cariprazine is an antipsychotic drug candidate for the potential treatment of schizophrenia, bipolar mania and depression

Uses

Cariprazine is an orally active D2/D3 dopamine receptor antagonist (1,2,3). Cariprazine is an antipsychotic drug candidate for the potential treatment of schizophrenia, bipolar mania and depression.

Definition

ChEBI: An N-alkylpiperazine that is N,N-dimethyl-N'-{trans-4-[2-(piperazin-1-yl)ethyl]cyclohexyl}urea substituted at position 4 on the piperazine ring by a 2,3-dichloroph nyl group. Used (as the hydrochloride salt) for treatment of schizophrenia and bipolar disorder.

CariprazineSupplier

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