Cariprazine
Cariprazine Basic information
- Product Name:
- Cariprazine
- Synonyms:
-
- Urea, N'-[trans-4-[2-[4-(2,3-dichlorophenyl)-1-piperazinyl]ethyl]cyclohexyl]-N,N -diMethyl-
- Cariprazine
- RGH 188;RGH188;RGH-188
- RGH 188;CARIPRAZINE;RGH188;RGH-188
- 3-[4-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]cyclohexyl]-1,1-dimethylurea
- N'-[trans-4-[2-[4-(2,3-Dichlorophenyl)-1-piperazinyl]ethyl]cyclohexyl]-N,N-dimethylurea
- RGH 188
- Cariprazine Cas No 839712-12-8 Qty1 gm
- CAS:
- 839712-12-8
- MF:
- C21H32Cl2N4O
- MW:
- 427.41
- EINECS:
- 1592732-453-0
- Product Categories:
-
- Aromatics
- Heterocycles
- Intermediates & Fine Chemicals
- Neurochemicals
- Pharmaceuticals
- Inhibitor
- CARIPRAZINE and Impurities
- API
- Mol File:
- 839712-12-8.mol
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Cariprazine Chemical Properties
- Melting point:
- >180°C (dec.)
- Density
- 1.24
- storage temp.
- -20°C Freezer, Under inert atmosphere
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- color
- Off-White to Light Beige
- InChI
- InChI=1S/C21H32Cl2N4O/c1-25(2)21(28)24-17-8-6-16(7-9-17)10-11-26-12-14-27(15-13-26)19-5-3-4-18(22)20(19)23/h3-5,16-17H,6-15H2,1-2H3,(H,24,28)/t16-,17-
- InChIKey
- KPWSJANDNDDRMB-QAQDUYKDSA-N
- SMILES
- N(C)(C)C(N[C@@H]1CC[C@@H](CCN2CCN(C3=CC=CC(Cl)=C3Cl)CC2)CC1)=O
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Safety Information
- Hazardous Substances Data
- 839712-12-8(Hazardous Substances Data)
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Cariprazine Usage And Synthesis
Uses
Cariprazine is an orally active D2/D3 dopamine receptor antagonist. Cariprazine is an antipsychotic drug candidate for the potential treatment of schizophrenia, bipolar mania and depression
Uses
Cariprazine is an orally active D2/D3 dopamine receptor antagonist (1,2,3). Cariprazine is an antipsychotic drug candidate for the potential treatment of schizophrenia, bipolar mania and depression.
Definition
ChEBI: An N-alkylpiperazine that is N,N-dimethyl-N'-{trans-4-[2-(piperazin-1-yl)ethyl]cyclohexyl}urea substituted at position 4 on the piperazine ring by a 2,3-dichloroph nyl group. Used (as the hydrochloride salt) for treatment of schizophrenia and bipolar disorder.
CariprazineSupplier
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