Cariprazine Impurity 3 Chemical Properties

Boiling point:

480.2±45.0 °C(Predicted)

Density 

1.171±0.06 g/cm3(Predicted)

storage temp. 

2-8°C, protect from light

solubility 

Chloroform (Slightly), Methanol (Slightly)

form 

Solid

pka

10.57±0.70(Predicted)

color 

Off-White to Pale Beige

Cariprazine Impurity 3 Usage And Synthesis

Uses

trans-4-[2-[4-(2,3-Dichlorophenyl)piperazin-1-yl]ethyl]cyclohexanamine, is an impurity of Cariprazine (C183490), an orally active D2/D3 dopamine receptor antagonist (1,2,3). Cariprazine is an antipsychotic drug candidate for the potential treatment of schizophrenia, bipolar mania and depression.

Cariprazine Impurity 3(791778-53-5)Related Product Information

• Desmethyl Cariprazine
• Piperazine, 1-(2-chloroethyl)-4-(2,3-dichlorophenyl)-
• Urea, N,N'-bis[trans-4-[2-[4-(2,3-dichlorophenyl)-1-piperazinyl]ethyl]cyclohexyl]-
• Urea, N,N-dimethyl-N'-[trans-4-[2-[[(4-methylphenyl)sulfonyl]oxy]ethyl]cyclohexyl]-
• ethyl dimethylcarbamate
• 3,3-dimethyl-1-[(1r,4r)-4-(2-hydroxyethyl)cyclohexyl]urea
• Cyclohexaneethanol, 4-amino-, hydrochloride (1:1), trans-
• Cariprazine
• Cariprazine-d6
• Cariprazine Impurity 4