2-Amino-3-pyridinecarboxaldehyde
2-Amino-3-pyridinecarboxaldehyde Basic information
- Product Name:
- 2-Amino-3-pyridinecarboxaldehyde
- Synonyms:
-
- 2-Aminopyridine-3-carboxaldehyde,98%
- 2-Amino-3-pyridinecarboxaldehyde 97%
- 2-AMINO-3-FORMYLPYRIDINE
- 2-AMINO-3-PYRIDINECARBOXALDEHYDE
- 2-AMINONICOTINALDEHYDE
- 2-AMINO-PYRIDIN-3-CARBALDEHYDE
- 2-AMINO-PYRIDINE-3-CARBALDEHYDE
- 2-AMINOPYRIDINE-3-CARBOXALDEHYDE
- CAS:
- 7521-41-7
- MF:
- C6H6N2O
- MW:
- 122.12
- EINECS:
- 626-730-5
- Product Categories:
-
- Aldehydes
- Building Blocks
- FINE Chemical & INTERMEDIATES
- Pyridine
- C6
- Heterocyclic Building Blocks
- pharmacetical
- Pyridine series
- Pyridines
- C1 to C6
- Carbonyl Compounds
- Chemical Synthesis
- Heterocyclic Building Blocks
- Organic Building Blocks
- Heterocycle-Pyridine series
- Pyrimidines
- Mol File:
- 7521-41-7.mol
2-Amino-3-pyridinecarboxaldehyde Chemical Properties
- Melting point:
- 98-102 °C (lit.)
- Boiling point:
- 290.7±25.0 °C(Predicted)
- Density
- 1.264±0.06 g/cm3(Predicted)
- Flash point:
- >300℃
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Soluble in Ether, Ethyl acetate, Chloroform (Slightly), Methanol (Slightly)
- pka
- 4.99±0.36(Predicted)
- form
- Powder, Crystals and/or Chunks
- color
- Yellow to light brown
- Water Solubility
- insoluble
- Sensitive
- Air Sensitive
- BRN
- 109598
- InChIKey
- NXMFJCRMSDRXLD-UHFFFAOYSA-N
- CAS DataBase Reference
- 7521-41-7(CAS DataBase Reference)
Safety Information
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-20/21/22
- Safety Statements
- 26-36-36/37/39
- WGK Germany
- 3
- HazardClass
- IRRITANT
- PackingGroup
- II
- HS Code
- 29339900
MSDS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ACROS
- Language:English Provider:ALFA
2-Amino-3-pyridinecarboxaldehyde Usage And Synthesis
Chemical Properties
yellow crystals
Uses
2-Aminonicotinaldehyde is commonly employed as a starting material for a wide variety of N-heterocyclic compounds (e.g. β-nicotyrine [N445000]) . 2-Aminonicotinaldehyde is also used as a reagent to synthesize hydrazones (e.g.thionaphthenquinone 3-hydrazone [T367720]), which possess antituburcular properties.
Preparation
Preparative Methods of 2-Amino-3-pyridinecarboxaldehyde: the reagent is best when freshly prepared. A multistep procedure starting from 2-amino-3-
picoline has been improved upon by a simple two-step approach. Sulfamation of nicotinamide with ammonium
sulfamate (both commercially available) provides 2-(3′-pyridyl)pyrido[2,3-d]pyridimine which may be
hydrolyzed in 2 N HCl to provide the reagent (eq 1)[1]. Substituted derivatives of the reagent may be prepared via
a similar intermediate.
storage
2-Amino-3-pyridinecarboxaldehyde is somewhat more stable than 2-Aminobenzaldehyde and may be stored for up to several months at 0 °C under an inert atmosphere. Sublimation is a convenient method for the separation of higher oligomers which may accumulate during storage. Use in a fume hood.
References
1. (a) Caluwe, P. T 1980, 36, 2359. (b) Cheng, C.-C.; Yan, S.-J. OR 1982, 28, 37. (c) Thummel, R. P. SL 1992, 1.
2-Amino-3-pyridinecarboxaldehydeSupplier
- Tel
- 021-37285141 15618858630
- yancf@yulibiotech.com
- Tel
- 21-58388037 13472507714
- 1589045147@qq.com
- Tel
- 86-27-82330560
- 2536851935@qq.com
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
- Tel
- 021-61259108 18621169109
- market03@meryer.com
2-Amino-3-pyridinecarboxaldehyde(7521-41-7)Related Product Information
- 4-Dimethylaminobenzaldehyde
- 2-Aminopyridine
- Molasses
- Glycine
- 2-Pyridinecarboxaldehyde
- 4-Pyridinecarboxaldehyde
- 2-Amino-3-picoline
- 4-Dimethylaminopyridine
- 4-Aminobenzaldehyde
- Betaine
- 3-Aminopyridine
- 3-Pyridinecarboxaldehyde
- ALTRENOGEST
- Nalidixic acid
- 2-Aminonicotinic acid
- Niflumic acid
- Amfonelic acid
- 2-ANILINONICOTINIC ACID