1,3-DICHLOROTETRAMETHYLDISILOXANE Chemical Properties

Melting point:

-37 °C

Boiling point:

138 °C (lit.)

Density 

1.039 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.407(lit.)

Flash point:

15 °C

storage temp. 

Flammables area

form 

liquid

Specific Gravity

1.038

color 

Colorless to Almost colorless

Water Solubility 

Reacts with water.

Sensitive 

Moisture Sensitive

Hydrolytic Sensitivity

8: reacts rapidly with moisture, water, protic solvents

BRN 

1741218

InChIKey

DMEXFOUCEOWRGD-UHFFFAOYSA-N

CAS DataBase Reference

2401-73-2(CAS DataBase Reference)

EPA Substance Registry System

Disiloxane, 1,3-dichloro-1,1,3,3-tetramethyl- (2401-73-2)

Safety Information

Hazard Codes 

F,C

Risk Statements 

11-34

Safety Statements 

16-26-27-36/37/39-45

RIDADR 

UN 2985 3/PG 2

WGK Germany 

3

F 

10-21

TSCA 

Yes

HazardClass 

3

PackingGroup 

II

HS Code 

29319090

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

1,3-DICHLOROTETRAMETHYLDISILOXANE Usage And Synthesis

Chemical Properties

clear colorless liquid

Uses

1,3-Dichlorotetramethyldisiloxane is used to produce 1,1,3,3-tetramethyl-disiloxane-1,3-diol. It is also used as Chemical Additives. Pharmaceutical intermediates.

Synthesis

General procedure: The chlorination reaction needs to be carried out in THF to ensure that all Si-H bonds are chlorinated, using TCCA as the chlorinating agent (molar ratio 1:1, TCCA:siloxane). This was done as follows: 1,1,3,3-tetramethyldisiloxane and THF (ratio 20 ml THF/g siloxane) were added to the reaction flask and the mixture was cooled to -20 °C. TCCA was added in batches with vigorous stirring, and after the addition of TCCA, stirring was continued for 15 min, after which the cooling bath was removed and the reaction mixture was allowed to warm slowly to room temperature. It should be noted that the chain length of the siloxane, the type of substituent and the position of the Si-H bond may affect the method of isolation and characterization of the subsequent products. Upon completion of the reaction, THF and unreacted TCCA should be removed immediately to avoid denaturation of the products during storage.

References

[1] Journal of Organometallic Chemistry, 2007, vol. 692, # 10, p. 1892 - 1897
[2] Journal of Organometallic Chemistry, 2018, vol. 875, p. 1 - 4
[3] Journal of the Chemical Society [Section] A: Inorganic, Physical, Theoretical, 1970, p. 1641 - 1642

1,3-DICHLOROTETRAMETHYLDISILOXANE(2401-73-2)Related Product Information

• 1,3-DI-N-OCTYLTETRAMETHYLDISILAZANE
• 1,3-DIMETHYLTETRAMETHOXYDISILOXANE
• 1,3-DIBUTYL-1,1,3,3-TETRAMETHYLDISILAZANE
• 1,3-DI-N-PROPYL-1,1,3,3-TETRAMETHYLDISILAZANE
• 1,3-DIETHYLTETRAMETHYLDISILOXANE
• 1,1,3,3-tetrachloro-1,3-dimethyldisiloxane
• 1,1,3,3-TETRAPHENYL-1,3-DIMETHYLDISILOXANE
• 1,1,3,5,5-Pentaphenyl-1,3,5-trimethyltrisiloxane
• TETRAETHYLCYCLOTETRASILOXANE
• 1,3-DICHLORO-1,3-DIMETHYL-1,3-DIPHENYLDISILOXANE
• 1,3-DICHLOROTETRAPHENYLDISILOXANE
• 1,1,3,3-TETRAMETHYLDISILOXANE
• Chlorodimethylsilane
• 1,1,3,3-Tetramethyldisiloxane
• 1,3-DICHLOROTETRAMETHYLDISILOXANE
• 1,3-DICHLORO-1,1,3,3-TETRAISOPROPYLDISILOXANE
• 1,1,3,3-TETRACYCLOPENTYLDICHLORODISILOXANE
• 1,3-DIVINYL-1,3-DIMETHYL-1,3-DICHLORODISILOXANE