PYRUVONITRILE Chemical Properties

Boiling point:

92-93 °C(lit.)

Density 

0.974 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.376(lit.)

Flash point:

58 °F

storage temp. 

2-8°C

solubility 

Soluble in ether and acetonitrile.

form 

Liquid

color 

Colorless to brown

BRN 

1737633

Exposure limits

NIOSH: IDLH 25 mg/m3

InChIKey

QLDHWVVRQCGZLE-UHFFFAOYSA-N

CAS DataBase Reference

631-57-2

Safety Information

Hazard Codes 

F,T,N

Risk Statements 

11-23/25-51/53-37/38

Safety Statements 

45-61-36/37-16

RIDADR 

UN 3273 3/PG 2

WGK Germany 

3

F 

8-10-13

HazardClass 

3.1

PackingGroup 

II

MSDS

• Language:English Provider:SigmaAldrich

PYRUVONITRILE Usage And Synthesis

Description

Pyruvonitrile is a versatile electrophile useful for selective acylation, cyanohydrin synthesis, and cycloaddition reactions.

Chemical Properties

Pyruvonitrile has a boiling point of 92.3 °C and a density of 0.9745 g/cm³.

Uses

Pyruvonitrile was used in the synthesis of cuprate-carbonyl π-complexes by reaction with Me2CuLi in THF.

Preparation

Preparative Methods of Pyruvonitrile: acyl cyanides are readily prepared from the reaction of acyl halides with Copper(I) Cyanide, Sodium Cyanide,or Cyanotrimethylsilane and via the oxidation of cyanohydrins.

General Description

The infrared spectra of pyruvonitrile was studied.

storage

Pyruvonitrile and its analogs are highly toxic; use in a fume hood.

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