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1-(5-Bromo-2-methoxy-phenyl)adamantane

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1-(5-Bromo-2-methoxy-phenyl)adamantane Basic information

Product Name:
1-(5-Bromo-2-methoxy-phenyl)adamantane
Synonyms:
  • 1-(5-BROMO-2-METHOXYPHENYL)TRYCYCLO[3,3,1,13,7]DECANE
  • 1-(5-bromo-2-methoxyphenyl)-tricyclo[3,3,1,13,7]decane (intermediate of adapalene)
  • 1-(5-Bromo-2-methoxyphenyl)adamantane 97%
  • 2-Adamantyl-4-bromo-1-methoxybenzene
  • 2-Adamantyl-4-bromoanisole
  • 2-(1-Adamantyl)-4-bromo-anisole (Adapalene)
  • TRICYCLO[3.3.1.13,7]DECANE, 1-(5-BROMO-2-METHOXYPHENYL)-
  • 1-(5-Bromo-2-methoxyphenyl)-tricyclo[3.3.1.13,7]decane
CAS:
104224-63-7
MF:
C17H21BrO
MW:
321.25
EINECS:
689-408-3
Product Categories:
  • API
  • Aromatics
  • Intermediates of Adapalene
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
  • blocks
  • Bromides
  • APIs Intermediate
  • Adamantane derivatives
  • ADAPALENE
  • (intermediate of adapalene)
Mol File:
104224-63-7.mol
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1-(5-Bromo-2-methoxy-phenyl)adamantane Chemical Properties

Melting point:
139-141°C
Boiling point:
402.5±38.0 °C(Predicted)
Density 
1.346±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly)
form 
Solid
color 
White
InChIKey
QQAMHHZQONQBFZ-UHFFFAOYSA-N
CAS DataBase Reference
104224-63-7(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Hazard Note 
Irritant
HS Code 
2909309090
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1-(5-Bromo-2-methoxy-phenyl)adamantane Usage And Synthesis

Description

1-(5-Bromo-2-methoxy-phenyl)adamantane is an organic synthesis reagent for the preparation of the adapalene intermediate 6-bromo-2-naphthalenecarboxylate.

Chemical Properties

1-(5-Bromo-2-methoxy-phenyl)adamantane Appearance is white Solid or white to light yellow powder to crystalline, melting point 144℃.

Uses

Adapalene (A225000) impurity.

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