(S)-2-Methyl-pyrrolidine Chemical Properties

Boiling point:

97-99 °C(lit.)

Density 

0.842 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.4354

Flash point:

45 °F

storage temp. 

2-8°C

pka

10.93±0.10(Predicted)

Appearance

Colorless to light yellow Liquid

optical activity

[α]20/D +19°, c = 5 in methanol

CAS DataBase Reference

59335-84-1(CAS DataBase Reference)

Safety Information

Hazard Codes 

F,C

Risk Statements 

11-22-34

Safety Statements 

26-36/37/39-45

RIDADR 

UN 2924 3/PG 2

WGK Germany 

2

Hazard Note 

Corrosive/Highly Flammable

PackingGroup 

Ⅱ

HS Code 

2933998090

(S)-2-Methyl-pyrrolidine Usage And Synthesis

Synthesis

The general procedure for the synthesis of 2-methylpyrrolidine from 2-methylpyrroline was as follows: whole-cell biotransformation reactions were carried out at 30 °C in a shaker at 1000 rpm in a sodium phosphate buffer (100 mM, pH 7.0). Freshly harvested resting cells of E. coli BL21(DE3) expressing IRED with a final OD600nm value of 90 were used.The reaction mixture contained 2.5 or 5 mM of imine substrate and 50 mM of glucose as co-substrate.

References

[1] Organic and Biomolecular Chemistry, 2010, vol. 8, # 20, p. 4533 - 4535
[2] Bioscience, Biotechnology and Biochemistry, 2011, vol. 75, # 9, p. 1778 - 1782
[3] ChemBioChem, 2013, vol. 14, # 11, p. 1372 - 1379
[4] ChemCatChem, 2015, vol. 7, # 4, p. 579 - 583
[5] Journal of Molecular Catalysis B: Enzymatic, 2014, vol. 110, p. 126 - 132

(S)-2-Methyl-pyrrolidine(59335-84-1)Related Product Information

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