D-(+)-DIGITOXOSE Chemical Properties

Melting point:

98-100 °C

alpha 

D17 +46.3° (in water); D20 +39.1° (in methanol); D18 +27.9° +43.3° (after 24 hrs in pyridine)

Boiling point:

188.74°C (rough estimate)

Density 

1.0610 (rough estimate)

refractive index 

1.4320 (estimate)

storage temp. 

Refrigerator

solubility 

DMSO (Slightly), Methanol (Slightly), Water (Slightly)

form 

Solid

pka

13.72±0.20(Predicted)

color 

White to Pale Yellow

optical activity

+46.4

CAS DataBase Reference

527-52-6(CAS DataBase Reference)

Safety Information

WGK Germany 

3

F 

3-10

HS Code 

29329990

MSDS

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D-(+)-DIGITOXOSE Usage And Synthesis

Uses

D-Digitoxose is a derivative of D-ribo-Hexonic acid that is metabolized in the liver. It inhibits glucose-stimulated insulin release.

Definition

ChEBI: Digitoxose is a dideoxyhexose.

Purification Methods

Crystallise D(+)-digitoxose from MeOH/Et2O, Et2O, EtOAc, EtOAc/Et2O/pet ether or Me2CO/Et2O and dry it over P2O5/vacuum. It has [] D +45.2o (6minutes) mutarotating to +50.2o (16hours constant) (c 1.65, H2O). [Gut & Prins Helv Chim Acta 20 1229 1947, Bollinger & Ulrich Helv Chim Acta 35 93 1952, NMR of derivs: Tsukamoto et al. J Chem Soc, Perkin Trans 1 2621 1988, Beilstein 1 IV 4191.]

D-(+)-DIGITOXOSE(527-52-6)Related Product Information

• GITOXIN
• 2-Hydroxypropyl-β-cyclodextrin
• beta-Cyclodextrin methyl ethers
• D-(+)-ALLOSE
• DIGOXIN
• CYMARIN
• SEDOHEPTULOSE ANHYDRIDE
• Digitoxin
• digitoxigenin+2digitoxose+acetyl-digilanidobos
• Bleomycin
• D-(+)-DIGITOXOSE
• LANATOSIDE B
• D-ALTROSE
• BETA-D-ALLOSE
• 20,22-Dihydrodigoxin
• HYDROXYETHYL BETA-CYCLODEXTRIN
• 2-ACETAMIDO-2-DEOXY-D-ALLOSE
• chalcomycin