UROTENSIN II (HUMAN)
UROTENSIN II (HUMAN) Basic information
- Product Name:
- UROTENSIN II (HUMAN)
- Synonyms:
-
- UROTENSIN II (HUMAN) HYDROCHLORIDE
- UROTENSIN II (HUMAN)
- ETPDCFWKYCV, HCL (DISULFIDE BRIDGE: 5-10)
- GLU-THR-PRO-ASP-CYS-PHE-TRP-LYS-TYR-CYS-VAL
- GLU-THR-PRO-ASP-CYS-PHE-TRP-LYS-TYR-CYS-VAL HYDROCHLORIDE
- Urotensin II human, ≥97% (HPLC)
- H-GLU-THR-PRO-ASP-CYS-PHE-TRP-LYS-TYR-CYS-VAL-OH, HCL (DISULFIDE BRIDGE: 5-10)
- H-GLU-THR-PRO-ASP-CYS-PHE-TRP-LYS-TYR-CYS-VAL-OH
- CAS:
- 251293-28-4
- MF:
- C64H85N13O18S2
- MW:
- 1388.57
- Product Categories:
-
- Peptide
- Urotensin receptor
- Mol File:
- 251293-28-4.mol
UROTENSIN II (HUMAN) Chemical Properties
- Boiling point:
- 1760.5±65.0 °C(Predicted)
- Density
- 1.46±0.1 g/cm3(Predicted)
- storage temp.
- -15°C
- pka
- 3.60±0.10(Predicted)
- form
- Solid
- biological source
- synthetic
- Water Solubility
- Soluble to 1 mg/ml in water
- Sequence
- Glu-Thr-Pro-Asp-Cys-Phe-Trp-Lys-Tyr-Cys-Val (Disulfide bridge: Cys5-Cys7)
- InChIKey
- HFNHAPQMXICKCF-USJMABIRSA-N
UROTENSIN II (HUMAN) Usage And Synthesis
Uses
Urotensin II human was used in agonist and antagonist preparation for calcium mobilization assay. The product can also be used as a test compound for studying the impact of dihydropyridine calcium antagonist amlodipine in human internal mammary artery and clinical implications.
Biochem/physiol Actions
Human urotensin II is a vasoactive neuropeptide that belongs to CRF family and stimulates arterial smooth muscle contraction, actin stress fiber formation and proliferation via small GTPase RhoA and there downstream effector Rho-kinase activation.The product is also a selective and potent vasoconstrictor agent as well as an agonist for the orphan receptor GPR14.
in vivo
Human Urotensin II (U-II) markedly increases total peripheral resistance in anaesthetized non-human primates, a response associated with profound cardiac contractile dysfunction[1].
storage
Desiccate at -20°C
UROTENSIN II (HUMAN)Supplier
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- 821-50328103-801 18930552037
- 3bsc@sina.com
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- 21-61263452 13641803416
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- 021-54306202 13764082696
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- 021-50135380
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- 0731-85526065 13308475853
- ivy@hnhbsj.com
UROTENSIN II (HUMAN)(251293-28-4)Related Product Information
- UROTENSIN-II
- Aviptadil
- UROTENSIN I
- FTLSLDVPTNIMNILFNIDKAKNLRAKAAANAQLMAQI-NH2
- STRESSCOPIN (3-40) (HUMAN) TRIFLUOROACETATE SALT
- urotensin II
- Uroguanylin Topoisomer B (human)
- Uroguanylin (human)
- UROCORTIN (RAT)
- STRESSCOPIN-RELATED PEPTIDE (6-43) (HUMAN) TRIFLUOROACETATE SALT
- UROCORTIN (HUMAN)
- Urotensin II (Frog)
- Urocortin II (mouse)
- Urotensin II,mouse TFA
- URODILATIN HUMAN
- Urotensin-2B
- Urocortin III, mouse, free acid
- Urotensin II (114-124), human TFA