UROCORTIN (RAT)
UROCORTIN (RAT) Basic information
- Product Name:
- UROCORTIN (RAT)
- Synonyms:
-
- Urocortin ratUrocortin
- Urocortin (sheep)
- Urocortin(Rattus norvegicus) (9CI)
- Urocortin 1 (rat)
- UROCORTIN (RAT)
- UROCORTIN (RAT) (FREE ACID)
- UROCORTIN (RAT) (MOUSE)
- H-ASP-ASP-PRO-PRO-LEU-SER-ILE-ASP-LEU-THR-PHE-HIS-LEU-LEU-ARG-THR-LEU-LEU-GLU-LEU-ALA-ARG-THR-GLN-SER-GLN-ARG-GLU-ARG-ALA-GLU-GLN-ASN-ARG-ILE-ILE-PHE-ASP-SER-VAL-NH2
- CAS:
- 171543-83-2
- MF:
- C206H338N62O64
- MW:
- 4707.26492
- Product Categories:
-
- Peptide
- CRFPeptides for Cell Biology
- CRF
- Neuropeptides
- Releasing Factors
- CRF receptor and related
- Mol File:
- 171543-83-2.mol
UROCORTIN (RAT) Chemical Properties
- storage temp.
- -20°C
- solubility
- 1% acetic acid: >1 mg/mL, clear, colorless
- form
- powder
- color
- White to off-white
- biological source
- rat
- Water Solubility
- Soluble to 1 mg/ml in water
- Sequence
- Asp-Asp-Pro-Pro-Leu-Ser-Ile-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Thr-Leu-Leu-Glu-Leu-Ala-Arg-Thr-Gln-Ser-Gln-Arg-Glu-Arg-Ala-Glu-Gln-Asn-Arg-Ile-Ile-Phe-Asp-Ser-Val-NH2
MSDS
- Language:English Provider:SigmaAldrich
UROCORTIN (RAT) Usage And Synthesis
Uses
Urocortin rat can be used for western blotting. The product can also be used for studying that whether CRF receptor type 2 (CRF2) and its high-affinity ligand, urocortin 1 (Ucn1) can mediate sex-specific cellular stress responses by using corticotropin-releasing factor receptor 2-deficient (Crhr2-/- ) and wild-type (WT) mice.
Biochem/physiol Actions
Urocortin is a CRF-related neuropeptide that binds to CRF receptor types 1α, 2α and 2β. It possesses appetite-suppressing effect. Urocortin along with corticotropin-releasing factor (CRF) binding protein (CRF-BP) enhances the free CRF levels in human brain by displacing hCRF from the binding protein.
in vivo
Urocortin, rat (0.01 to 10 μg) decreases food intake in both food-deprived and non-deprived rats and such an effect also observed in mice after 1 μg of Urocortin, rat i.c.v. administration. Urocortin, rat has the potential of inducing anxiogenic behavior[3].
IC 50
CRFR1; CRFR2
UROCORTIN (RAT)Supplier
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- 821-50328103-801 18930552037
- 3bsc@sina.com
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- 21-61263452 13641803416
- ymbetter@glbiochem.com
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- 021-54306202 13764082696
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- 021-50135380
- shchemsky@sina.com
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- 0731-85526065 13308475853
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UROCORTIN (RAT)(171543-83-2)Related Product Information
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- UROTENSIN I
- STRESSCOPIN-RELATED PEPTIDE (6-43) (HUMAN) TRIFLUOROACETATE SALT
- UROCORTIN (HUMAN)
- Urocortin II (mouse)
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- Urolithin A
- Urolithin C
- PHENYLSELENOL
- N-BUTYLISOCYANIDE
- Cupric acetylacetonate
- TERT-BUTYL ISOCYANIDE
- DICHLORO(ETHYLENEDIAMINE)PLATINUM(II)