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DL-4-HYDROXYPHENYLGLYCINE

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DL-4-HYDROXYPHENYLGLYCINE Basic information

Product Name:
DL-4-HYDROXYPHENYLGLYCINE
Synonyms:
  • DL-4-OH-Phg-OH
  • 4-HYDROXY-DL-PHENYLGLYCINE
  • 2-Amino-2-(4-hydroxyphenyl)aceticacid
  • (4-Hydroxyphenyl)(amino)acetic acid
  • 2-(4-Hydroxyphenyl)glycine
  • 2-amino-2-(4-hydroxyphenyl)acetic acid (en)
  • 4-[Amino(carboxy)methyl]phenol
  • 4-[Amino(carboxy)methyl]phenol, Amino(4-hydroxyphenyl)acetic acid
CAS:
938-97-6
MF:
C8H9NO3
MW:
167.16
EINECS:
213-353-2
Product Categories:
  • pharmacetical
  • Pharmaceutical Intermediates
  • bc0001
Mol File:
938-97-6.mol
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DL-4-HYDROXYPHENYLGLYCINE Chemical Properties

Melting point:
229-230 °C
Boiling point:
365.8±32.0 °C(Predicted)
Density 
1.396±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
DMSO (Very Slightly, Heated), Water (Slightly, Heated, Sonicated)
form 
Solid
pka
2.15±0.10(Predicted)
color 
White to Pale Yellow
InChI
InChI=1S/C8H9NO3/c9-7(8(11)12)5-1-3-6(10)4-2-5/h1-4,7,10H,9H2,(H,11,12)
InChIKey
LJCWONGJFPCTTL-UHFFFAOYSA-N
SMILES
C(C1C=CC(O)=CC=1)(N)C(=O)O
CAS DataBase Reference
938-97-6(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
HazardClass 
IRRITANT
HS Code 
2918290090
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DL-4-HYDROXYPHENYLGLYCINE Usage And Synthesis

Chemical Properties

Type R (i.e. D): crystalline, melting point 240°C (decomposition), [α]-158.4° (C=1,1 mol/L HCl). (+/-) type: lamellar crystals (water), insoluble in water, insoluble in ether, 200°C non-melting decomposition.

Uses

(4-Hydroxyphenyl)glycine, is a key intermediate for the synthesis Cefpiramide (C243400), used as a β-lactam antibiotic.

Uses

4-hydroxyphenylglycine is used (now only rarely) as a photographic developer and in the determination of phosphorus and silicon.

Definition

ChEBI: 4-hydroxyphenylglycine is a glycine molecule carrying a 4-hydroxyphenyl substituent. It has a role as a bacterial metabolite. It is functionally related to a glycine.

Synthesis Reference(s)

Journal of the American Chemical Society, 93, p. 2897, 1971 DOI: 10.1021/ja00741a013

DL-4-HYDROXYPHENYLGLYCINE Preparation Products And Raw materials

Raw materials

DL-4-HYDROXYPHENYLGLYCINESupplier

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