ChemicalBook > Product Catalog > Biochemical Engineering > Amino Acids and Derivatives > Glycine derivative > 4-Hydroxy-L-phenylglycine
4-Hydroxy-L-phenylglycine
4-Hydroxy-L-phenylglycine Basic information
- Product Name:
- 4-Hydroxy-L-phenylglycine
- Synonyms:
-
- H-PHG(4-HYDROXY)-OH
- H-HPG-OH
- L-(+)-A-4-HYDROXYPHENYLGLYCINE
- L-4-HYDROXYPHENYLGLYCINE
- L-(+)-P-HYDROXYPHENYLGLYCINE
- L-NORTYR
- 4-HYDROXY-L-PHENYLGLYCINE
- (S)-AMINO-(4-HYDROXY-PHENYL)-ACETIC ACID
- CAS:
- 32462-30-9
- MF:
- C8H9NO3
- MW:
- 167.16
- EINECS:
- 251-061-7
- Product Categories:
-
- Amino ACIDS SERIES
- Mol File:
- 32462-30-9.mol
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4-Hydroxy-L-phenylglycine Chemical Properties
- Melting point:
- ~240 °C (dec.)
- alpha
- 158 º (c=1% in 1M HCl)
- Boiling point:
- 365.8±32.0 °C(Predicted)
- Density
- 1.396±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- Aquous Acid (Slightly), DMSO (Slightly, Heated, Sonicated), Water (Slightly)
- pka
- 2.15±0.10(Predicted)
- form
- Solid
- color
- White to Off-White
- optical activity
- [α]20/D +158±3°, c = 1% in 1 M HCl
- BRN
- 3589845
- InChI
- InChI=1/C8H9NO3/c9-7(8(11)12)5-1-3-6(10)4-2-5/h1-4,7,10H,9H2,(H,11,12)/t7-/s3
- InChIKey
- LJCWONGJFPCTTL-ZETCQYMHSA-N
- SMILES
- [C@@H](C1C=CC(O)=CC=1)(N)C(=O)O |&1:0,r|
- CAS DataBase Reference
- 32462-30-9(CAS DataBase Reference)
- EPA Substance Registry System
- Benzeneacetic acid, .alpha.-amino-4-hydroxy-, (.alpha.S)- (32462-30-9)
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Safety Information
- Hazard Codes
- Xn
- Risk Statements
- 22-36/37/38
- Safety Statements
- 26-36
- WGK Germany
- 3
- HS Code
- 2922.50.4000
MSDS
- Language:English Provider:SigmaAldrich
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4-Hydroxy-L-phenylglycine Usage And Synthesis
Chemical Properties
White crystalline
Uses
Vasodilator.
Uses
4-Hydroxy-L-(+)-2-phenylglycine is a carnitine palmitoyltransferase-1 inhibitor. 4-Hydroxy-L-(+)-2-phenylglycine improves whole-body glucose tolerance and insulin sensitivity in high-fat diet-induced obese mouse with insulin resistance.
Definition
ChEBI: The L-enantiomer of 4-hydroxyphenylglycine.
reaction suitability
reaction type: solution phase peptide synthesis
in vivo
Oxfenicine (150 mg/kg, i.p., once daily for 3 weeks) treatment significantly reduces adiposity in high-fat diet rats[4].
| Animal Model: | Male Sprague-Dawley rats fed a high-fat (HF) diet[4] |
| Dosage: | 150 mg/kg |
| Administration: | intraperitoneal injection (i.p.) once daily for 3 weeks |
| Result: | Reduced whole-body fat oxidation, body weight, adiposity, and improved insulin sensitivity in HF-fed rats. |
4-Hydroxy-L-phenylglycineSupplier
Shanghai Chiral Chemicals Inc. Gold
- Tel
- 021-37285021 13472570865
- tym7xi@aliyun.com
J & K SCIENTIFIC LTD.
- Tel
- 18210857532; 18210857532
- jkinfo@jkchemical.com
TCI (Shanghai) Development Co., Ltd.
- Tel
- 021-67121386
- Sales-CN@TCIchemicals.com
Energy Chemical
- Tel
- 021-021-58432009 400-005-6266
- sales8178@energy-chemical.com
Capot Chemical Co., Ltd
- Tel
- +86 (0) 571 85 58 67 18
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4-Hydroxy-L-phenylglycine(32462-30-9)Related Product Information
- D-4-Hydroxyphenylglycine Methyl ester hydrochloride
- METHYL 2-AMINO-2-(4-HYDROXYPHENYL)ACETATE
- 4-HYDROXY-DL-PHENYLGLYCINE
- Potassium (R)-((3-ethoxy-1-methyl-3-oxoprop-1-enyl)amino)(4-hydroxyphenyl)acetate
- 4-Hydroxy-D-(-)-2-phenylglycine
- HYDROXY-N-PHENYLGLYCINE
- L-Phenylglycine
- Glycine
- Methyl 4-nitrobenzoate
- D-(-)-A-4-HYDROXYPHENYLGLYCINE DANE SALT METHYL POTASSIUM
- DL-P-Hydroxyphenylglycine
- 4-Hydroxy-D-phenylglycine methyl ester
- 4-carboxy-3-hydroxy-L-phenylglycine
- BOC-4-HYDROXY-D-PHENYLGLYCINE
- FMOC-4-HYDROXY-D-PHENYLGLYCINE
- parahydroxy phenylglycine dane salt
- 4-Hydroxy-L-phenylglycine methyl ester
- N-L-α-Aspartyl-4-hydroxy-D-phenylglycine 1-[(1S)-1,3,3-trimethylbicyclo[2.2.1]heptan-2α-yl] ester