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1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride

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1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride Basic information

Product Name:
1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride
Synonyms:
  • 1-(1,4-benzodioxan-2-ylcarbonyl)piperazine hydrochloride
  • N-[(1,4-Benzodioxin-2-yl)carbonyl]piperazine hydrochloride
  • 2-(1-Piperazinylcarbonyl)-1,4-benzodioxane Hydrochloride
  • 4-Benzodioxan-2-carbonyl)-piperazine hydrochloride
  • Doxazosin Related Compound A (20 mg) (N-(1,4-benzodioxane-2-carbonyl)piperazine hydrochloride)
  • Methanone,(2,3-dihydro-1,4-benzodioxin-2-yl)-1-piperazinyl-, hydrochloride (1:1)
  • (2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)(piperazin-1-yl)Methanone hydrochloride
  • N-(1,4-Benzodioxane-2-carbonyl)piperazine Hydrochloride
CAS:
70918-74-0
MF:
C13H17ClN2O3
MW:
284.74
EINECS:
415-660-9
Product Categories:
  • (intermediate of doxazosin)
  • (intermediate of doxazocin mesylate)
  • Piperidines, Piperidones, Piperazines
Mol File:
70918-74-0.mol
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1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride Chemical Properties

Melting point:
105-108°C
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
powder to crystal
color 
White to Almost white
Stability:
Hygroscopic
CAS DataBase Reference
70918-74-0(CAS DataBase Reference)
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Safety Information

Hazard Codes 
T;N,Xi,N,T
Risk Statements 
23/24/25-48/22-51/53
Safety Statements 
45-53-61
RIDADR 
UN2811 - class 6.1 - PG 3 - EHS - Toxic solids, organic, n.o.s., HI: all
Hazard Note 
Irritant
HazardClass 
6.1
PackingGroup 
III
HS Code 
2934990002
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1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride Usage And Synthesis

Uses

1-[(2,3-Dihydro-1,4-benzodioxin-2-yl)carbonyl]piperazine Monohydrochloride (Doxazosin EP Impurity B) is an impurity of Doxazosin (D537500), a selective a1-adrenoceptor antagonist. Doxazosin relaxes smooth muscles of the prostate.

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