5-Amino-4-imidazolecarboxamide
5-Amino-4-imidazolecarboxamide Basic information
- Product Name:
- 5-Amino-4-imidazolecarboxamide
- Synonyms:
-
- 4-AMINOIMIDAZOLE-5-CARBOXAMIDE
- 4-amino-5-imidazolecarboxamid
- 5-amino-1h-imidazole-4-carboxamid
- 5-Amino-4-glyoxalinecarboxamide
- 5-amino-imidazole-4-carboxamid
- 5-amino-4-imidazolecarboxamide
- 5-AMINOIMIDAZOLE-4-CARBOXAMIDE
- 5-AMINO-1H-IMIDAZOLE-4-CARBOXAMIDE
- CAS:
- 360-97-4
- MF:
- C4H6N4O
- MW:
- 126.12
- EINECS:
- 206-641-4
- Product Categories:
-
- Amines
- Amines, Metabolites & Impurities, Nucleotides, Bases & Related Reagents
- pharmacetical
- Building Blocks
- Heterocyclic Building Blocks
- Imidazoles
- Imidazol&Benzimidazole
- Various Metabolites and Impurities
- Bases & Related Reagents
- Metabolites & Impurities
- Nucleotides
- bc0001
- Mol File:
- 360-97-4.mol
5-Amino-4-imidazolecarboxamide Chemical Properties
- Melting point:
- 164-170 °C(lit.)
- Boiling point:
- 234.22°C (rough estimate)
- Density
- 1.3659 (rough estimate)
- refractive index
- 1.8500 (estimate)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly), Water (Slightly)
- pka
- 11.97±0.10(Predicted)
- form
- Powder
- color
- White
- Water Solubility
- Soluble in DMSO, Methanol, Water.
- InChI
- InChI=1S/C4H6N4O/c5-3-2(4(6)9)7-1-8-3/h1H,5H2,(H2,6,9)(H,7,8)
- InChIKey
- DVNYTAVYBRSTGK-UHFFFAOYSA-N
- SMILES
- C1NC(N)=C(C(N)=O)N=1
- CAS DataBase Reference
- 360-97-4(CAS DataBase Reference)
- EPA Substance Registry System
- 1H-Imidazole-4-carboxamide, 5-amino- (360-97-4)
MSDS
- Language:English Provider:SigmaAldrich
5-Amino-4-imidazolecarboxamide Usage And Synthesis
Description
5-Amino-4-imidazolecarboxamide may be used in the synthesis of 4-(N′-benzoylcarbamoyl)amino-5-imidazolecarboxamide and 5-amino-1-β-D-ribosyl-4-imidazolecarboxamide-5′-phosphate (AICAR).It is an imidazole derivative which is a metabolite of the antineoplastic agents BIC and DIC. By itself, or as the ribonucleotide, it is used as a condensation agent in the preparation of nucleosides and nucleotides. When compounded with orotic acid, it is used to treat liver diseases.
Reference
3. Black, S. L., M. J. Black, and J. H. Mangum. "A rapid assay for 5-amino-4-imidazolecarboxamide ribotide transformylase." Analytical Biochemistry90.1(1978):397-401.
Chemical Properties
White to Off-White Solid
Uses
A metabolite of Temozolomide
Uses
4-Aminoimidazole-5-carboxamide is used as Catalytic agent, Petrochemical additive. It is metabolite of temozolomide.
Uses
5-Amino-4-imidazolecarboxamide may be used in the synthesis of 4-(N′-benzoylcarbamoyl)amino-5-imidazolecarboxamide and 5-amino-1-β-D-ribosyl-4-imidazolecarboxamide-5′-phosphate (AICAR).
Definition
ChEBI: An aminoimidazole in which the amino group is at C-5 with a carboxamido group at C-4.
5-Amino-4-imidazolecarboxamide Preparation Products And Raw materials
Raw materials
Preparation Products
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5-Amino-4-imidazolecarboxamide(360-97-4)Related Product Information
- ALTRENOGEST
- Formamide
- Glycine
- Chlorantraniliprole
- 4-Aminoimidazole
- Benzamide
- N,N-Dimethylformamide
- Betaine
- 4-diazo-4H-imidazole-5-carboxamide
- Cyano temozolomide
- 5-(Amino-1-(N-methyl Carbamoyl)
- Temozolomide
- Temozolomideacid
- 3-Amino-2-(formylamino)-3-iminopropanamide
- Cyanotemozolomide
- TeMozoloMide Metabolite - MTIC
- 1,5-dihydro-4H-imidazo[4,5-d]-1,2,3-triazin-4-one
- 1,7-DIMETHYLXANTHINE