DAGO Chemical Properties

Boiling point:

922.7±65.0 °C(Predicted)

Density 

1.271±0.06 g/cm3(Predicted)

storage temp. 

-15°C

solubility 

≥40.7 mg/mL in EtOH; ≥40.7 mg/mL in H2O; ≥42.2 mg/mL in DMSO

form 

solid

pka

9.97±0.15(Predicted)

color 

White

Water Solubility 

Soluble in water (4 mM)

Sequence

H-Tyr-D-Ala-Gly-NMe-Phe-Gly-ol

Stability:

Hygroscopic

DAGO Usage And Synthesis

Uses

DAMGO is an opioid receptor agonist (1,2). DAMGO can be used to investigate the analgesic mechanism of opioids. It has been shown that DAMGO can modulate the two-pore domain K(+) channels in the substantia gelatinosa neurons (3).

Definition

ChEBI: (D-Ala(2)-mephe(4)-gly-ol(5))enkephalin is a peptide.

Biological Activity

Highly selective peptide agonist for the μ opioid receptor.

storage

-20°C (desiccate)

DAGO(78123-71-4)Related Product Information

• DAMGO [TYROSYL-3,5-3H, (DAGO)]
• ([125I]-TYR)-DAGO
• guanyl-DAMME
• DAGO [TYROSYL-3,5-3H]
• DAGO ACETATE SALT,DAGO, DAMGO, Tyr-D-Ala-Gly-N-methyl-Phe-Gly-ol
• FK 33-824
• [3,5-DIIODO-TYR1]-DAGO,(3,5-DIIODO-TYR1)-DAGO ACOH,(3,5-DIIODO-TYR1)-DAGO ACETATE SALT,3,5-Diiodo-Tyr-D-Ala-Gly-N-Methyl-Phe-Gly-ol, [3,5-Diodo-Tyr1]-DAGO
• DAGO