3-(2-(2-Azidoethoxy)ethoxy)prop-1-yne Usage And Synthesis

Uses

Azido-PEG2-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG2-propargyl is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-1008. DOI:10.1016/j.cell.2020.07.024

3-(2-(2-Azidoethoxy)ethoxy)prop-1-yne(1245006-63-6)Related Product Information

• 3-(2-Methoxyethoxy)prop-1-yne
• INDEX NAME NOT YET ASSIGNED
• Propargyl-PEG2-t-butyl ester
• Propargyl-PEG2-Maleimide
• Propargyl-PEG2-methylamine