Remoxipride Chemical Properties

alpha 

D20 -64° (c = 2 in ethanol)

Boiling point:

439.9±45.0 °C(Predicted)

Density 

1.292

storage temp. 

2-8°C

pka

pKa 8.9 (Uncertain)

CAS DataBase Reference

80125-14-0(CAS DataBase Reference)

NIST Chemistry Reference

Remoxipride(80125-14-0)

Remoxipride Usage And Synthesis

Uses

Antipsychotic.

Definition

ChEBI: 3-bromo-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2,6-dimethoxybenzamide is a dimethoxybenzene.

General Description

Remoxipride is a D₂ receptorblocker.It is as effective as haloperidol with fewer EPS andautonomic side effects. Negative symptoms of schizophreniaare diminished. The drug is classed as an atypical antipsychotic.Life-threatening aplastic anemia was reported with itsuse, which prompted its withdrawal from the market.
With respect to the atypical antipsychotics, two eventslong in the past may shed some light on the events of today.
The field of reuptake-inhibiting antidepressants arose whenonly a very small structural change was made in an antipsychoticdrug, and the new activity noted. (The antipsychoticactivity remained.) Therefore, small changes in structurecan produce antipsychotics that are active against depressivesymptoms. Likewise, small changes in structure could provideselectivity among D₂ receptors.

Remoxipride(80125-14-0)Related Product Information

• Kresoxim-methyl
• Methylparaben
• p-(2-Methoxyethyl) phenol
• Methyl acrylate
• Methanol
• Benzamide
• Basic Violet 1
• 3-Bromoanisole
• Methyl acetate
• Chlorantraniliprole
• Paraquat dichloride
• Acetonitrile
• Methyl
• 3-BROMO-2-METHOXYBENZALDEHYDE
• 3-Bromo-N-butylbenzamide
• 5-Bromo-2-chlorobenzoic acid
• BENZAMIDE, N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-2-HYDROXY-6-METHOXY-, (S)-
• N-(5-BROMO-2-METHOXYBENZYL)-N-METHYLAMINE