CHRYSOMYCIN A
CHRYSOMYCIN A Basic information
- Product Name:
- CHRYSOMYCIN A
- Synonyms:
-
- 6H-Benzo[d]naphtho[1,2-b]pyran-6-one,4-(6-deoxy-3-C-methyl-b-gulopyranosyl)-8-ethenyl-1-hydroxy-10,12-dimethoxy-(9CI)
- 8-ethenyl-1-hydroxy-10,12-dimethoxy-4-(3,4,5-trihydroxy-4,6-dimethyloxan-2-yl)naphtho[1,2-c]isochromen-6-one
- (+)-4-(6-Deoxy-3-C-methyl-β-D-gulo-hexopyranosyl)-8-ethenyl-1-hydroxy-10,12-dimethoxy-6H-benzo[d]naphtho[1,2-b]pyran-6-one
- (+)-Virenomycin V
- Chrysomycin V
- Virenomycin V
- 4-(6-Deoxy-3-C-methyl-beta-gulopyranosyl)-8-ethenyl-1-hydroxy-10,12-dimethoxy-6H-benzo[d]naphtho[1,2-b]pyran-6-one
- NSC 613946
- CAS:
- 82196-88-1
- MF:
- C28H28O9
- MW:
- 508.52
- Product Categories:
-
- Inhibits an EnzymeEnzyme Inhibitors by Enzyme
- Topoisomerase II
- A - KAntibiotics
- Antibacterial
- Antibiotics A to
- Antibiotics A-FAntibiotics
- Antibiotics by Application
- Antineoplastic and Immunosuppressive AntibioticsAntibiotics
- Mechanism of Action
- R to
- Spectrum of Activity
- Mol File:
- 82196-88-1.mol
CHRYSOMYCIN A Chemical Properties
- Boiling point:
- 799.7±60.0 °C(Predicted)
- Density
- 1.405±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMF: soluble
- pka
- 8.55±0.20(Predicted)
- form
- solid
- color
- Yellow to greenish
CHRYSOMYCIN A Usage And Synthesis
Uses
Chrysomycin A is a potent antibacterial, antifungal and antiviral compound.
Uses
Chrysomycin A is the major analogue in a complex of C-glycoside antitumour actives isolated from Streptomyces. Chrysomycin A, with a vinyl group in the 8-position, is the most potent analogue of the complex, and is thought to act as an inhibitor of the catalytic activity of human topoisomerase II. Chrysomyin A has a potent antibacterial, antifungal, antiviral and antitumour profile. More recent research on related metabolites, the gilvocarcins, suggests that chrysomycins may act as photoactivated, crosslinkers of DNA to histones.
Uses
Chrysomycin A is the major analogue in a complex of C-glycoside antitumor actives isolated from Streptomyces. Chrysomycin A, with a vinyl group in the 8-position, is the most potent analogue of the complex, and is thought to act as an inhibitor of the catalytic activity of human topoisomerase II. Chrysomycin A has a potent antibacterial, antifungal, antiviral and antitumor profile. More recent research on related metabolites, the gilvocarcins, suggests that chrysomycins may act as photoactivated cross-linkers of DNA to histones.
Definition
ChEBI: Chrysomycin a is a glycoside.
storage
+4°C
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