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CHRYSOMYCIN A

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CHRYSOMYCIN A Basic information

Product Name:
CHRYSOMYCIN A
Synonyms:
  • 6H-Benzo[d]naphtho[1,2-b]pyran-6-one,4-(6-deoxy-3-C-methyl-b-gulopyranosyl)-8-ethenyl-1-hydroxy-10,12-dimethoxy-(9CI)
  • 8-ethenyl-1-hydroxy-10,12-dimethoxy-4-(3,4,5-trihydroxy-4,6-dimethyloxan-2-yl)naphtho[1,2-c]isochromen-6-one
  • (+)-4-(6-Deoxy-3-C-methyl-β-D-gulo-hexopyranosyl)-8-ethenyl-1-hydroxy-10,12-dimethoxy-6H-benzo[d]naphtho[1,2-b]pyran-6-one
  • (+)-Virenomycin V
  • Chrysomycin V
  • Virenomycin V
  • 4-(6-Deoxy-3-C-methyl-beta-gulopyranosyl)-8-ethenyl-1-hydroxy-10,12-dimethoxy-6H-benzo[d]naphtho[1,2-b]pyran-6-one
  • NSC 613946
CAS:
82196-88-1
MF:
C28H28O9
MW:
508.52
Product Categories:
  • Inhibits an EnzymeEnzyme Inhibitors by Enzyme
  • Topoisomerase II
  • A - KAntibiotics
  • Antibacterial
  • Antibiotics A to
  • Antibiotics A-FAntibiotics
  • Antibiotics by Application
  • Antineoplastic and Immunosuppressive AntibioticsAntibiotics
  • Mechanism of Action
  • R to
  • Spectrum of Activity
Mol File:
82196-88-1.mol
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CHRYSOMYCIN A Chemical Properties

Boiling point:
799.7±60.0 °C(Predicted)
Density 
1.405±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMF: soluble
pka
8.55±0.20(Predicted)
form 
solid
color 
Yellow to greenish
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Safety Information

WGK Germany 
3
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CHRYSOMYCIN A Usage And Synthesis

Uses

Chrysomycin A is a potent antibacterial, antifungal and antiviral compound.

Uses

Chrysomycin A is the major analogue in a complex of C-glycoside antitumour actives isolated from Streptomyces. Chrysomycin A, with a vinyl group in the 8-position, is the most potent analogue of the complex, and is thought to act as an inhibitor of the catalytic activity of human topoisomerase II. Chrysomyin A has a potent antibacterial, antifungal, antiviral and antitumour profile. More recent research on related metabolites, the gilvocarcins, suggests that chrysomycins may act as photoactivated, crosslinkers of DNA to histones.

Uses

Chrysomycin A is the major analogue in a complex of C-glycoside antitumor actives isolated from Streptomyces. Chrysomycin A, with a vinyl group in the 8-position, is the most potent analogue of the complex, and is thought to act as an inhibitor of the catalytic activity of human topoisomerase II. Chrysomycin A has a potent antibacterial, antifungal, antiviral and antitumor profile. More recent research on related metabolites, the gilvocarcins, suggests that chrysomycins may act as photoactivated cross-linkers of DNA to histones.

Definition

ChEBI: Chrysomycin a is a glycoside.

storage

+4°C

CHRYSOMYCIN ASupplier

Taizhou Zhongzhi Biotechnology Co., Ltd Gold
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Guangzhou Isun Pharmaceutical Co., Ltd
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