Basic information Safety Supplier Related

TAMOXIFEN-N-OXIDE

Basic information Safety Supplier Related

TAMOXIFEN-N-OXIDE Basic information

Product Name:
TAMOXIFEN-N-OXIDE
Synonyms:
  • TAMOXIFEN-N-OXIDE
  • (Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine-N-oxide
  • Ethanamine, 2-(4-(1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethyl-, N-oxide, (Z)-
  • Tamoxifen epoxide
  • 2-[4-[(1Z)-1,2-Diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethylethanamine N-oxide
  • Ethanamine, 2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethyl-, N-oxide
  • Tamoxifen Citrate Impurity 12 (Tamoxifen N-oxide)
CAS:
75504-34-6
MF:
C26H29NO2
MW:
387.51
Product Categories:
  • Aromatics
  • Nitric Oxide Reagents
  • Various Metabolites and Impurities
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
  • Protein Kinase Inhibitors and Activators
Mol File:
75504-34-6.mol
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TAMOXIFEN-N-OXIDE Chemical Properties

storage temp. 
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility 
DMF: 20 mg/mL; DMSO: 2 mg/mL; Ethanol: 20 mg/mL; Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/mL
form 
A crystalline solid
pka
4.49±0.40(Predicted)
color 
White to off-white
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TAMOXIFEN-N-OXIDE Usage And Synthesis

Chemical Properties

White Solid

Uses

A metabolite of Tamoxifen, a nonsteroidal estrogen antagonist of interest in the treatment of some forms of breast cancer. Tamoxifen is a Protein Kinase C inhibitor, and induces apoptosis in human malignant glioma cell lines

Definition

ChEBI: An N-oxide derived from tamoxifen.

TAMOXIFEN-N-OXIDESupplier

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