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N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture)

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N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture) Basic information

Product Name:
N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture)
Synonyms:
  • 4-[1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol
  • 4OHNDtam
  • E/Z Endoxifen
  • N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture)
  • 4-hydroxy-N-desmethyltamoxifen
  • 4-[(E)-1-[4-(2-methylaminoethoxy)phenyl]-2-phenyl-but-1-enyl]phenol
  • 4-[(Z)-1-[4-[2-(Methylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol
  • N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture) see H938500
CAS:
110025-28-0
MF:
C25H27NO2
MW:
373.49
Product Categories:
  • Aromatics
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
Mol File:
110025-28-0.mol
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N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture) Chemical Properties

Melting point:
63-72°C
Boiling point:
519.3±50.0 °C(Predicted)
Density 
1.099±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Chloroform, Dichloromethane, DMSO, Methanol
form 
Solid
pka
9.38±0.15(Predicted)
color 
Light Brown to Light Purple
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N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture) Usage And Synthesis

Chemical Properties

Brown Foam

Uses

A novel active metabolite of the anti-cancer drug Tamoxifen. It showed potent ER binding property, blocked estrogen stimulated growth of breast cancer cell and half maximal inhibition of estrogen responsive gene expression in ER pos. human breast ca

Uses

A novel active metabolite of the anti-cancer drug Tamoxifen (T006000). It showed potent ER binding property, blocked estrogen stimulated growth of breast cancer cell and half maximal inhibition of estrogen responsive gene expression in ER pos. human breast cancer cell line.

storage

Store at +4°C

N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture)Supplier

Beijing LAL Pharmaceutical Co., Ltd. Gold
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010-010-62452898 13581984929
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J & K SCIENTIFIC LTD.
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Nanjing Chemlin Chemical Co., Ltd
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