4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID
4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID Basic information
- Product Name:
- 4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID
- Synonyms:
-
- 4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID
- 2,2'-(1,2-Ethenediyl)bis(5-isothiocyanatobenzenesulfonic acid)
- 4,4'-Bis(isothiocyanato)stilbene-2,2'-bissulfonic acid
- 4,4'-Diisothiocyanato-2,2'-stilbenedisulfonic acid
- 4,4'-Diisothiocyano-2,2'-stilbenedisulfonic acid
- 4,4′-Diisotbiocyano-2,2′-stilbenedisulfnic Acid Disodium Salt
- 5-isothiocyanato-2-[(E)-2-(4-isothiocyanato-2-sulfophenyl)ethenyl]benzenesulfonic acid
- Benzenesulfonic acid,2,2'-(1,2-ethenediyl)bis[5-isothiocyanato-
- CAS:
- 53005-05-3
- MF:
- C16H10N2O6S4
- MW:
- 454.52
- Product Categories:
-
- Cross Linking Reagents
- Fluorescent Labels & Indicators
- Mol File:
- 53005-05-3.mol
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4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID Chemical Properties
- Melting point:
- >400°C
- Density
- 1.54±0.1 g/cm3(Predicted)
- pka
- -1.32±0.50(Predicted)
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4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID Usage And Synthesis
Chemical Properties
Yellow Crystalline Solid
Uses
Stilbene disulfonates have been employed to inhibit anion transport in a large number of mammalian cell types (GABA, Cl-). Some stilbene disulfonates can bind specifically to proteins that are not anion transporters. DIDS reacts with CD4 glycoprot
Uses
Ion channel inhibitor; especially of anion transport.
Definition
ChEBI: 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid is an arenesulfonic acid.
General Description
Binds covalently and irreversibly to the outer surface of human erythrocyte membranes. Inhibits ATP transport into endoplasmic reticulum vesicles. Anion transport inhibitor that inhibits Cl– uptake (IC50 = 150 nM) in neuroblastoma cells. Has anti-ulcerous properties.
Biochem/physiol Actions
Primary TargetCl- uptake
4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACIDSupplier
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4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID(53005-05-3)Related Product Information
- 4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID, DISODIUM SALT (DIDS)
- 4,4'-DIAMINOSTILBENE DIHYDROCHLORIDE
- 4,4'-DIISOTHIOCYANATO-2,2'-STILBENEDISULFONIC ACID, DISODIUM SALT HYDRATE
- 4,4'-Diamino-2,2'-stilbenedisulfonic acid
- 4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid disodium salt hydrate
- P-VINYLPHENYL ISOTHIOCYANATE
- 4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID