2-acetamido-3-methyl-3-(nitrososulfanyl)butanoic acid Chemical Properties

Melting point:

150.5°C

Density 

1.4261 (rough estimate)

refractive index 

1.5400 (estimate)

RTECS 

YV9383000

storage temp. 

-20°C

solubility 

H₂O: ≥2 mg/mL

pka

3.06±0.10(Predicted)

form 

powder

color 

green

CAS DataBase Reference

67776-06-1(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

2-acetamido-3-methyl-3-(nitrososulfanyl)butanoic acid Usage And Synthesis

Description

SNAP is an S-nitrosothiol which serves as a NO donor and a potent vasodilator. Its stability in solution varies from seconds to hours depending on temperature, buffer composition and metal content. At pH 6-8 and 37°C, the half-life of SNAP is approximately six hours in the presence of transition metal ion chelators.

Chemical Properties

2-acetamido-3-methyl-3-(nitrososulfanyl)butanoic acid is green crystalline solid

Uses

Produced concentration-related relaxations of mouse anococcygeus, in a range similar to that already found for NO and other nitrovasodilators. A potent relaxant of non-vascular smooth muscle. Serves as an NO donor.

Biochem/physiol Actions

NO donor; vasodilator, smooth muscle relaxant, lymphocyte activator. Activates soluble guanylyl cyclase.

2-acetamido-3-methyl-3-(nitrososulfanyl)butanoic acid(67776-06-1)Related Product Information

• NORPSEUDOEPHEDRINE HCL SNAP-N-SHOOT 0.1MG/ML(REAGENT / STANDARD GRADE),NORPSEUDOEPHEDRINE HCL SNAP-N-SHOOT 1.0MG/ML(SECONDARY STANDARD)
• S-NITROSO-N-ACETYLPENICILLAMINE (SNAP) P OTENT VASODILATOR
• ROSIN SNAP-N-SHOOT 0.1MG/ML(SECONDARY STANDARD)
• ANTI-ALPHA/BETA-SNAP
• TPX SNAP RING VIALS, (11,6 X 32 MM) WITH INTEGRATED 0,2 ML GLASS MICRO-INSERT, 15 MM TIP, PACK á 100 EA
• TRIBULOSAPONIN B SNAP-N-SHOOT 0.1MG/ML(P)
• Α/Β-SNAP MONOCLONAL ANTIBODY
• HYDROXYVALERENIC ACID SNAP-N-SHOOT 0.1MG/ML(SECONDARY STANDARD)
• 11MM POLYPROPYLENE PRE-CUT SNAP ON CAP
• SNAP TOGETHER TEST TUBE RACK FOR 13 MM
• HYPERFORIN SNAP-N-SHOOT 0.1MG/ML(SECONDARY STANDARD)
• SNAP-ON ALL-PURPOSE LABORATORY TOOL KIT&
• RED CLOVER SNAP-N-SHOOT KIT (SECONDARY STANDARD)
• 1.5 ML EVAPOVIAL SNAP CAP COMBO PACK 100/PACK
• SNAP-SEAL PP SAMPLE CONTAINER 300ML
• VALERENIC ACID SNAP-N-SHOOT 0.1MG/ML(SECONDARY STANDARD)
• FORMONONETIN SNAP-N-SHOOT 0.1MG/ML(SECONDARY STANDARD)
• EPHEDRA EPHEDRINE ALKALOID SNAP-N-SHOOT KIT 12