Basic information Safety Supplier Related

4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINE

Basic information Safety Supplier Related

4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINE Basic information

Product Name:
4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINE
Synonyms:
  • 4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINE
  • 4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINE###162012-70-6
  • 4-chloro-6-nitro-7-fluoro-quinazoline
  • Afatinib impurity 6: 4-chloro-7fluoro-6-nitroquinazoline
  • Quinazoline, 4-chloro-7-fluoro-6-nitro-
CAS:
162012-70-6
MF:
C8H3ClFN3O2
MW:
227.58
EINECS:
000-000-0
Mol File:
162012-70-6.mol
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4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINE Chemical Properties

Boiling point:
395℃
Density 
1.649
Flash point:
193℃
storage temp. 
Sealed in dry,Store in freezer, under -20°C
pka
0.53±0.70(Predicted)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22-36
Safety Statements 
26
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4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINE Usage And Synthesis

Uses

4-Chloro-7-fluoro-6-nitroquinazoline is an intermediate in the synthesis of Afatinib (A355300), an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.

4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINESupplier

Anhui Dexinjia Biopharm Co., Ltd Gold
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0531-82375887 13596650888
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3385307203@qq.com
JinYan Chemicals(ShangHai) Co.,Ltd.
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13817811078
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sales@jingyan-chemical.com
Adamas Reagent, Ltd.
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400-6009262 16621234537
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zhangsn@titansci.com
Nanjing Chemlin Chemical Co., Ltd
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025-83697070
Email
info@chemlin.com.cn
Shanghai Ennopharm Co., Ltd.
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+86 (21) 6435-5022