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TRANS-4-AMINOCROTONIC ACID

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TRANS-4-AMINOCROTONIC ACID Basic information

Product Name:
TRANS-4-AMINOCROTONIC ACID
Synonyms:
  • (E)-4-AMINO-2-BUTENOIC ACID
  • (6r-trans)-7-amino-8-oxo-3-[(1h-1,2,3-triazol-4-ylthio)methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • TRANS-4-AMINOCROTONIC ACID
  • trans-4-Aminocrotonic acid, TACA
  • Afatinib impurity 42
  • Afatinib Impurity 71
  • 2-Butenoic acid, 4-amino-, (2E)-
  • (E)-4-aminobut-2-enoic acid
CAS:
38090-53-8
MF:
C4H7NO2
MW:
101.1
EINECS:
253-547-4
Product Categories:
  • GABA/Glycine receptor
Mol File:
38090-53-8.mol
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TRANS-4-AMINOCROTONIC ACID Chemical Properties

Melting point:
174-176 °C (decomp)
Boiling point:
300.4±25.0 °C(Predicted)
Density 
1.169±0.06 g/cm3(Predicted)
storage temp. 
Store at RT
solubility 
H2O: >20 mg/mL
form 
solid
pka
3.65±0.10(Predicted)
color 
white
Water Solubility 
Soluble to 100 mM in water
Stability:
Light Sensitive, Temperature Sensitive, Unstable in Solution
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Safety Information

Safety Statements 
22-24/25
WGK Germany 
3

MSDS

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TRANS-4-AMINOCROTONIC ACID Usage And Synthesis

Uses

TACA is a GABAA?and GABAC?agonist or antagonist for use in the treatment of vascular diseases, also used in the studies on cancer vaccines and carbohydrate epitopes.

Biological Activity

The trans-isomer of CACA. Potent GABA A agonist, GABA uptake inhibitor and substrate for GABA-T. Also GABA C agonist.

storage

Store at RT

TRANS-4-AMINOCROTONIC ACIDSupplier

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