3-[(2-METHYL-1,3-THIAZOL-4-YL)ETHYNYL]PYRIDINE
3-[(2-METHYL-1,3-THIAZOL-4-YL)ETHYNYL]PYRIDINE Basic information
- Product Name:
- 3-[(2-METHYL-1,3-THIAZOL-4-YL)ETHYNYL]PYRIDINE
- Synonyms:
-
- 3-[(2-METHYL-1,3-THIAZOL-4-YL)ETHYNYL]PYRIDINE
- MTEP
- 3-(2-Methyl-thiazol-4-ylethynyl)-pyridine
- 2-methyl-4-(pyridin-3-ylethynyl)thiazole
- 3-[2-(2-Methyl-1,3-thiazol-4-yl)ethynyl]pyridine
- 2-methyl-4-(2-pyridin-3-ylethynyl)-1,3-thiazole
- Pyridine, 3-[(2-methyl-4-thiazolyl)ethynyl]-
- MTEP hydrochloride >=98% (HPLC)
- CAS:
- 329205-68-7
- MF:
- C11H8N2S
- MW:
- 200.26
- Mol File:
- Mol File
More
Less
3-[(2-METHYL-1,3-THIAZOL-4-YL)ETHYNYL]PYRIDINE Chemical Properties
- Boiling point:
- 360.7±17.0 °C(Predicted)
- Density
- 1.26±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- methanol: 1mg/mL
DMSO: 5mg/mL - pka
- 3.41±0.12(Predicted)
- form
- White to yellow solid.
- color
- white to yellow
More
Less
3-[(2-METHYL-1,3-THIAZOL-4-YL)ETHYNYL]PYRIDINE Usage And Synthesis
Uses
MTEP Hydrochloride is a potent mGlu5 receptor antagonist, acting as a negative allosteric modulator.
Biological Activity
Cell permeable: yes', 'Primary Target
mGluR5', 'Product does not compete with ATP.', 'Reversible: no', 'Target IC50: 5 nM in Ca2+-flux assay', 'Target Ki: 16 nM for mGluR5 (metabotropic glutamate receptor subtype-5)
3-[(2-METHYL-1,3-THIAZOL-4-YL)ETHYNYL]PYRIDINESupplier
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
Shanghai Tauto Biotech Co., Ltd.
- Tel
- 021-51320588
- tauto@tautobiotech.com
Jiaxing Novartis Chemical Co., Ltd.
- Tel
- 18957373295
Sigma-Aldrich
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
ShangHai Angti Biotechnology Co., Ltd.
- Tel
- 13764913901
- info@angtibio.com