2,4,6-Trichloroaniline Chemical Properties

Melting point:

73-75 °C (lit.)

Boiling point:

262 °C (lit.)

Density 

1.6807 (rough estimate)

vapor pressure 

0-0.631Pa at 25℃

refractive index 

1.6300 (estimate)

Flash point:

262°C

storage temp. 

Storage temperature: no restrictions.

solubility 

0.039g/l slightly soluble

pka

0.07±0.10(Predicted)

color 

Needles or liquid from pet ether

Water Solubility 

<0.1 g/100 mL at 21.5 ºC

BRN 

879568

Stability:

Stable, but may be light or air sensitive. Incompatible with acids, acid chlorides, acid anhydrides, chloroformates, strong oxidizing agents.

InChIKey

NATVSFWWYVJTAZ-UHFFFAOYSA-N

LogP

3.648-3.69 at 25℃

CAS DataBase Reference

634-93-5(CAS DataBase Reference)

NIST Chemistry Reference

Benzenamine, 2,4,6-trichloro-(634-93-5)

EPA Substance Registry System

2,4,6-Trichloroaniline (634-93-5)

Safety Information

Hazard Codes 

T,N

Risk Statements 

23/24/25-33-50/53

Safety Statements 

28-36/37-45-60-61-28A

RIDADR 

UN 2811 6.1/PG 2

WGK Germany 

3

RTECS 

BZ0250000

Hazard Note 

Toxic

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

II

HS Code 

29214200

Hazardous Substances Data

634-93-5(Hazardous Substances Data)

Toxicity

LD50 orl-rat: 2400 mg/kg GISAAA 55(6),86,90

MSDS

• Language:English Provider:2,4,6-Trichloroaniline
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

2,4,6-Trichloroaniline Usage And Synthesis

Chemical Properties

fine purple fibres

Uses

2,4,6-trichloroaniline is important as an intermediate in the manufacture of benzene derivatives, including 1,3,5-trichlorobenzene and is useful in the formation of fungicides, mono-azo dyestuffs, and the preparation of hexachlorodiphenyl urea.
Tetrachloronitrobenzene was prepared from 2:4:6-trichloroaniline,which was converted by a Sandmeyer reaction into 1:2:3:5- tetrachlorobenzene.

Preparation

2,4,6-Trichloroaniline can be prepared by reaction of dry aniline with chlorine gas while in a anhydrous solution of carbon tetrachloride. 2,4,6-Trichloroaniline precipitates from solution as a white solid. If water is introduced to the solution the white material will polymerize to form aniline black.
Process for the preparation of 2,4,6-trichloroaniline

General Description

Long needles or fine, light purple fibers.

Air & Water Reactions

2,4,6-Trichloroaniline may be sensitive to exposure to light and air. Insoluble in water.

Reactivity Profile

2,4,6-Trichloroaniline is incompatible with acids, acid chlorides, acid anhydrides, chloroformates, and strong oxidizing agents. .

Fire Hazard

Flash point data for 2,4,6-Trichloroaniline are not available. 2,4,6-Trichloroaniline is probably combustible.

Safety Profile

Moderately toxic by ingestion.Irritant. Questionable carcinogen with experimentalcarcinogenic data. Mutation data reported. When heatedto decomposition it emits very toxic fumes of Clí andNOx.

Purification Methods

Crystallise the aniline from ligroin. The benzoyl derivative has m 174o (from EtOH). [Beilstein 12 H 627, 12 IV 1281.]

2,4,6-Trichloroaniline (634-93-5)Related Product Information

• 4-Chloroaniline
• 3-Chloroaniline
• 3,4-Dichloroaniline
• 2,5-Dichloroaniline
• 2,6-Dichloroaniline
• 2-Chloroaniline
• 2,4-Dichloroaniline
• 2,4,5-TRICHLOROANILINE,2,4,5-Trichloroaniline,97%,2,4,5-Trichloroaniline, tech., 97%,2,4,5-TRICHLOROANILINE PESTANAL
• 2,4,6-TRICHLORONITROBENZENE
• Quintozine
• Pentachloroaniline
• 1-(2,4,6-Trichlorophenyl)-3-amino-pyrazolin-5-one
• 2,4,6-TRICHLOROPHENYL ISOCYANATE
• 2,4,6-TRICHLOROPHENYL ISOTHIOCYANATE
• 1-(2,4,6-TRICHLOROPHENYL)-2-THIOUREA
• DICHLORPHENAMIDE BULK POWDER
• 2,4,5-Trichloroaniline hydrochloride
• 1,3,5-trichloro-2,4-dinitrobenzene