Basic information Uses Sources Safety Supplier Related

(R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid

Basic information Uses Sources Safety Supplier Related

(R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid Basic information

Product Name:
(R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid
Synonyms:
  • (r)-(-)-3-(2-amino-2-oxoethyl)-5-methylhexanoic acid
  • (r)-(-)-3-carbamoymethyl-5-methylhexanoic acid
  • INTERMEDIATE OF PREGABALIN
  • (3R)-3-(2-AMino-2-oxoethyl)-5-Methylhexanoic Acid
  • (R)-3-(2-AMINO-2-OXOETHYL)-5-METHYLHEXANOIC ACID:99+%
  • 3-CarbaMoyl Mehyl-5-Methyl Hexanoic Acid
  • Pregabalin IMpurity III
  • Hexanoic acid,3-(2-aMino-2-oxoethyl)-5-Methyl-,(3R)-
CAS:
181289-33-8
MF:
C9H17NO3
MW:
187.24
EINECS:
605-923-8
Product Categories:
  • Aliphatics, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
  • intermidiate of Pregablin
  • Starting Raw Materials & Intermediates
  • 181289-33-8
Mol File:
181289-33-8.mol
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(R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid Chemical Properties

Melting point:
128-133°C
Boiling point:
401.9±28.0 °C(Predicted)
Density 
1.080±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
4.68±0.10(Predicted)
color 
White to Off-White
CAS DataBase Reference
181289-33-8(CAS DataBase Reference)
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(R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid Usage And Synthesis

Uses

(R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid is a useful chemical intermediate for manufacturing of the anticonvulsant drug, Pregabalin1, 2.

Sources

  1. https://quod.lib.umich.edu/a/ark/5550190.0011.a22?rgn=main;view=fulltext
  2. https://www.researchgate.net/publication/269660675_Synthesis_and_characterization_of_impurities_of_an_anticonvulsant_drug_Pregabalin

Chemical Properties

White Solid

Uses

An Impurity of the anti-convulsant (S)-Pregabalin (P704790).

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