timonacic sodium
timonacic sodium Basic information
- Product Name:
- timonacic sodium
- Synonyms:
-
- timonacic sodium
- 4-Thiazolidinecarboxylic acid sodium salt
- CAS:
- 35041-11-3
- MF:
- C4H7NO2S.Na
- MW:
- 0
- EINECS:
- 252-332-2
- Mol File:
- 35041-11-3.mol
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timonacic sodium Usage And Synthesis
Originator
Hepaldine,Riker,France,1964
Manufacturing Process
Cysteine is first dissolved in distilled water which has been freed of oxygen by boiling. Formaldehyde of 30% (w/v) concentration is added while stirring and the temperature of the mixture rises, while the thiazolidine carboxylic acid begins crystallizing. The stirring is continued for 2 hours after which ethyl alcohol of 95% (w/v) concentration is added to induce further crystallization. The mixture is left to stand for 24 hours at 4°C. The mixture is then filtered with retention of a crude product, which is purified by recrystallization from boiling distilled water. The crystals are then dried at about 40°C. The free acid is then converted to the sodium salt with NaOH.
Therapeutic Function
Hepatoprotectant, Choleretic
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