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2-Bromobutyric acid methyl ester

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2-Bromobutyric acid methyl ester Basic information

Product Name:
2-Bromobutyric acid methyl ester
Synonyms:
  • 2-BROMOBUTYRIC ACID METHYL ESTER
  • 2-BROMO-N-BUTYRIC ACID METHYL ESTER
  • Methyl-2-bromo butryrate
  • 2-Bromomethylbutyrate
  • METHYL 2-BROMOBUTYRATE, 1X1ML, MTBE, &
  • Methyl2-bromobutyrate,97%
  • (R,S)-2-Bromo-butyric acid methyl ester
  • 2-bromo-butanoic acid methyl ester
CAS:
3196-15-4
MF:
C5H9BrO2
MW:
181.03
EINECS:
221-699-0
Product Categories:
  • ester series
  • 500 Series Drinking Water Methods
  • EPA
  • Method 552
  • C2 to C5
  • Carbonyl Compounds
  • Esters
  • bc0001
Mol File:
3196-15-4.mol
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2-Bromobutyric acid methyl ester Chemical Properties

Melting point:
116 °C
Boiling point:
137-138 °C/50 mmHg (lit.)
Density 
1.573 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.452(lit.)
Flash point:
155 °F
storage temp. 
Inert atmosphere,Room Temperature
form 
clear liquid
color 
Colorless to Light yellow
Specific Gravity
1.573
Water Solubility 
Soluble in alcohol and ether, slightly soluble in water.
BRN 
1720826
CAS DataBase Reference
3196-15-4(CAS DataBase Reference)
EPA Substance Registry System
Methyl 2-bromobutyrate (3196-15-4)
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Safety Information

Hazard Codes 
C,Xi,F
Risk Statements 
34-38-11
Safety Statements 
26-36/37/39-45-24-16-9
RIDADR 
UN 3265 8/PG 3
WGK Germany 
3
19
TSCA 
Yes
HazardClass 
8
PackingGroup 
III
HS Code 
29159000

MSDS

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2-Bromobutyric acid methyl ester Usage And Synthesis

Chemical Properties

clear slightly yellow liquid

Uses

Methyl 2-bromobutyrate is used in the synthesis of racemic indene ester via Reformatsky reaction with 5-methoxy-1-indanone. (E)-2-methoxymethylene-butyric acid methyl ester via reformatsky reaction with α,α-dichloromethyl methyl ether in the presence of zinc dust.

Uses

Methyl 2-bromobutyrate has been employed as reagent in the synthesis of:

  • racemic indene ester via Reformatsky reaction with 5-methoxy-1-indanone
  • (E)-2-methoxymethylene-butyric acid methyl ester via Reformatsky reaction with α,α-dichloromethyl methyl ether in the presence of zinc dust
  • (E)-2-methoxymethylene-butyryl chloride

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