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Hydroxy Bosentan

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Hydroxy Bosentan Basic information

Product Name:
Hydroxy Bosentan
Synonyms:
  • 4-(2-Hydroxy-1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-benzenesulfonamide
  • Ro 48-863
  • Ro 48-8634
  • Bosentan HydroxyMethyl IMpurity
  • Bosentan Hydroxy
  • Bosentan-Hydroxy methyl-Imp
  • N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]-4-(1-hydroxy-2-methylpropan-2-yl)benzenesulfonamide
  • Benzenesulfonamide, 4-(2-hydroxy-1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-
CAS:
253688-60-7
MF:
C27H29N5O7S
MW:
567.61
Product Categories:
  • Aromatics
  • Heterocycles
  • Bases & Related Reagents
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Nucleotides
  • Pharmaceuticals
  • Sulfur & Selenium Compounds
Mol File:
253688-60-7.mol
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Hydroxy Bosentan Chemical Properties

Melting point:
128-132°C
Boiling point:
783.9±70.0 °C(Predicted)
Density 
1.372±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer, Under Inert Atmosphere
solubility 
DMSO: soluble
form 
A crystalline solid
pka
3.90±0.10(Predicted)
color 
White to off-white
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Safety Information

HS Code 
29339900
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Hydroxy Bosentan Usage And Synthesis

Chemical Properties

Hydroxy Bosentan is White Powder

Uses

Hydroxy Bosentan is a metabolite of Bosentan, a mixed endothelin receptor antagonist which is used as a vasodilator

Uses

The active metabolite of Bosentan, a mixed endothelin receptor antagonist which is used as a vasodilator.

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