ChemicalBook > Product Catalog > Chemical Reagents > Organic reagents > Aromatic acids > N-methylisatoic anhydride
N-methylisatoic anhydride
N-methylisatoic anhydride Basic information
- Product Name:
- N-methylisatoic anhydride
- Synonyms:
-
- N-methyl isotoic anhydride
- Isatoic anhydride, N-Methyl-
- N-Methylisatioc anhydride
- 1-methyl-1H-benzo[d][1,3]oxazine-2,4-dione
- 1-Methyl-1,2-dihydro-4H-3,1-benzoxazine-2,4-dione
- 1-Methyl-1H-3,1-benzoxazine-2,4-dione
- 1-Methyl-4H-3,1-benzoxazine-2(1H),4-dione
- N-Methylisatoic anhydride,90%,tech.
- CAS:
- 10328-92-4
- MF:
- C9H7NO3
- MW:
- 177.16
- EINECS:
- 233-714-8
- Product Categories:
-
- Monomers
- Polymer Science
- pharmacetical
- Anhydride Monomers
- Mol File:
- 10328-92-4.mol
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N-methylisatoic anhydride Chemical Properties
- Melting point:
- 165 °C (dec.)(lit.)
- Boiling point:
- 309.06°C (rough estimate)
- Density
- 1.3312 (rough estimate)
- vapor density
- 6.1 (vs air)
- refractive index
- 1.5200 (estimate)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Soluble in DMSO
- pka
- -2.24±0.20(Predicted)
- Sensitive
- Moisture Sensitive
- CAS DataBase Reference
- 10328-92-4(CAS DataBase Reference)
- EPA Substance Registry System
- 2H-3,1-Benzoxazine-2,4(1H)-dione, 1-methyl- (10328-92-4)
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MSDS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ACROS
- Language:English Provider:ALFA
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N-methylisatoic anhydride Usage And Synthesis
Chemical Properties
brownish chunks
Uses
N-Methylisatoic anhydride is a 2'-OH selective acylation agent of RNAs, and is widely used for resolving secondary RNA structures using the SHAPE (Selective 2'-Hydroxyl Acylation Analyzed by Primer Extension) technology.
Definition
ChEBI: N-methylisatoic anhydride is a 3,1-benzoxazin-1,4-dione having an N-methyl substituent.
Application
N-Methylisatoic anhydride was first condensed with ethanolamine to give N-(2-hydroxyethyl)-2-methylaminobenzamide. Cyclization of the latter with ethyl pyruvate gave quinazoline derivatives which, upon hydrolysis and dehydrative cyclization with l-methyl-2-chloropyridinium iodide, afforded the l,4-oxazines[3,4-]quinazoline.
N-methylisatoic anhydrideSupplier
Shanghai Rlavie Technology Co., Ltd. Gold
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- 021-021-67759270 17717059219
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J & K SCIENTIFIC LTD.
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- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
Alfa Aesar
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- 400-6106006
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TCI (Shanghai) Development Co., Ltd.
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- 021-67121386
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Energy Chemical
- Tel
- 021-021-58432009 400-005-6266
- sales8178@energy-chemical.com
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N-methylisatoic anhydride(10328-92-4)Related Product Information
- 5-Chloro-N-methylisatoic anhydride
- N-methylisatoic anhydride
- Ethyl 4-dimethylaminobenzoate
- Isatoic Anhydride
- 1-ISOPROPYL-1H-BENZO[D][1,3]OXAZINE-2,4-DIONE
- N-BENZYLISATOIC ANHYDRIDE
- 5-CHLORO-1-METHYL-1H-BENZO[D][1,3]OXAZINE-2,4-DIONE
- 3-METHOXY-N-METHYLISATOIC ANHYDRIDE
- N-ALLYLISATOIC ANHYDRIDE
- 6-Methylisatoic anhydride
- 5-METHYLISATOIC ANHYDRIDE
- 7-FLUORO-2-METHYLISATOIC ANHYDRIDE
- AMILORIDE, 5-(N-METHYL-N-ISOBUTYL) (MIA) >97% EXTREMELY POTE,MIA
- 6-CHLORO-N-METHYLISATOIC ANHYDRIDE
- N-METHYLISATOIC ANHYDRIDE POLYSTYRENE (100-200 MESH, 3 MMOL/G)
- HUMAN MIA
- KG POA 5-METHYLISATOIC ANHYDRIDE
- MIA protein