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humantenmine

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humantenmine Basic information

Product Name:
humantenmine
Synonyms:
  • humantenmine
  • Spiro[3H-indole-3,7'(6'H)-[3,6]methano[3H]oxepino[4,3-b]pyrrol]-2(1H)-one, 2'-ethyl-3'a,4',8',8'a-tetrahydro-1-methoxy-, (3S,3'R,3'aS,6'R,8'aS)-
CAS:
82354-38-9
MF:
C19H22N2O3
MW:
326.39
Product Categories:
  • Alkaloids
Mol File:
82354-38-9.mol
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humantenmine Chemical Properties

Boiling point:
463.6±55.0 °C(Predicted)
Density 
1.44±0.1 g/cm3(Predicted)
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Cryst.
pka
7.17±0.20(Predicted)
color 
Off-white to light yellow
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humantenmine Usage And Synthesis

Chemical Properties

Colorless block crystal (acetone), melting point 166 ~ 168℃, soluble in benzene, chloroform and alcohols and other organic solvents.

Biological Activity

Humantenmine, an alkaloid isolated from Chinese nematode, has potential for pain and rheumatoid arthritis.

in vitro

Humantenmine (HMT) decreases the 14-day survival rate of the mice to 17% after they are intragastrically treated with HMT, along with hepatic injury and increasing alanine aminotransferase (ALT)/aspartate aminotransferase (AST) levels. CYP3A4/5 mediates the metabolism and detoxification of HMT.

target

P450 (e.g. CYP17)

humantenmineSupplier

Chengdu Greenpure Biopharma CO.,Ltd Gold
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028-88203606; 18283602253
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Chengdu Gupte Biotechnology Co., Ltd. Gold
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13881890404
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2851503757@qq.com
Chembest Research Laboratories Limited
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+86-21-20908456
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BioBioPha Co., Ltd.
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0871-65217109 13211707573;
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y.liu@mail.biobiopha.com
Chengdu Biopurify Phytochemicals Ltd.
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+86-028-82633397 18982077548
Email
cwb1@biopurify.cn
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humantenmine(82354-38-9)Related Product Information