ranaconitine
ranaconitine Basic information
- Product Name:
- ranaconitine
- Synonyms:
-
- ranaconitine
- 20-Ethyl-1α,14α,16β-trimethoxyaconitane-4,7,8,9-tetrol 4-[2-(acetylamino)benzoate]
- 4-[2-(Acetylamino)benzoyloxy]-20-ethyl-1α,14α,16β-trimethoxyaconitane-7,8,9-triol
- O4-(2-Acetamidobenzoyl)ranaconine
- (1alpha,14alpha,16beta)-Aconitane-4,7,8,9-tetrol 20-ethyl-1,14,16-trimethoxy-4-[2-(acetylamino)benzoate]
- 7-Hydroxylappaconitine
- Ranaconitine（85%）
- Aconitane-4,7,8,9-tetrol, 20-ethyl-1,14,16-trimethoxy-, 4-[2-(acetylamino)benzoate], (1α,14α,16β)-
- CAS:
- 1360-76-5
- MF:
- C32H44N2O9
- MW:
- 600.7
- Mol File:
- 1360-76-5.mol
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ranaconitine Chemical Properties
- Melting point:
- 132-134℃
- Boiling point:
- 758.9±60.0 °C(Predicted)
- Density
- 1.39
- storage temp.
- Store at -20°C
- solubility
- DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml; DMSO: 10 mg/ml; Ethanol: 1 mg/ml
- form
- A solid
- pka
- 12.08±0.70(Predicted)
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ranaconitine Usage And Synthesis
Occurrence
An aconitine alkaloid, ranaconitine occurs in the ethanolic extract of the Bulgarian plant Aconitum ranunculaefolium. It forms colourless needles when crystallized from EtOH and is dextrorotatory with a specific rotation of [α]D +33.2° (c 0.5, CHCI3 ). Hydrolysis with 5% KOH furnishes ranaconine, C23H37NO7 , m.p. 107-109°C and N-acetylanthranilic acid.
Uses
Ranaconitine is an important diterpenoid alkaloid from Aconitum sinomontanum and displayspotential anti-inflammatory analgesic activity as well as antagonism and modulation of voltage-gated Na+ channels.
Definition
ChEBI: S-(2-aminoethyl)isothiourea is an imidothiocarbamic ester.
ranaconitineSupplier
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