Basic information Safety Supplier Related

ranaconitine

Basic information Safety Supplier Related

ranaconitine Basic information

Product Name:
ranaconitine
Synonyms:
  • ranaconitine
  • 20-Ethyl-1α,14α,16β-trimethoxyaconitane-4,7,8,9-tetrol 4-[2-(acetylamino)benzoate]
  • 4-[2-(Acetylamino)benzoyloxy]-20-ethyl-1α,14α,16β-trimethoxyaconitane-7,8,9-triol
  • O4-(2-Acetamidobenzoyl)ranaconine
  • (1alpha,14alpha,16beta)-Aconitane-4,7,8,9-tetrol 20-ethyl-1,14,16-trimethoxy-4-[2-(acetylamino)benzoate]
  • 7-Hydroxylappaconitine
  • Ranaconitine(85%)
  • Aconitane-4,7,8,9-tetrol, 20-ethyl-1,14,16-trimethoxy-, 4-[2-(acetylamino)benzoate], (1α,14α,16β)-
CAS:
1360-76-5
MF:
C32H44N2O9
MW:
600.7
Mol File:
1360-76-5.mol
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ranaconitine Chemical Properties

Melting point:
132-134℃
Boiling point:
758.9±60.0 °C(Predicted)
Density 
1.39
storage temp. 
Store at -20°C
solubility 
DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml; DMSO: 10 mg/ml; Ethanol: 1 mg/ml
form 
A solid
pka
12.08±0.70(Predicted)
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ranaconitine Usage And Synthesis

Occurrence

An aconitine alkaloid, ranaconitine occurs in the ethanolic extract of the Bulgarian plant Aconitum ranunculaefolium. It forms colourless needles when crystallized from EtOH and is dextrorotatory with a specific rotation of [α]D +33.2° (c 0.5, CHCI3 ). Hydrolysis with 5% KOH furnishes ranaconine, C23H37NO7 , m.p. 107-109°C and N-acetylanthranilic acid.

Uses

Ranaconitine is an important diterpenoid alkaloid from Aconitum sinomontanum and displayspotential anti-inflammatory analgesic activity as well as antagonism and modulation of voltage-gated Na+ channels.

Definition

ChEBI: S-(2-aminoethyl)isothiourea is an imidothiocarbamic ester.

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