ethylene dimethanesulfonate Chemical Properties

Melting point:

35-36 °C

Boiling point:

328.93°C (rough estimate)

Density 

1.400 (estimate)

refractive index 

1.5630 (estimate)

storage temp. 

Sealed in dry,Room Temperature

solubility 

Chloroform (Sparingly, Heated), Methanol (Very Slightly)

form 

Solid

color 

White to Off-White

ethylene dimethanesulfonate Usage And Synthesis

Uses

Ethylene dimethane sulfonate is a mild alkylating, non-volatile methanesulfonic diester of ethylene glycol. Ethylene dimethanesulfonate has selective pro-apoptotic effects on LCs[1].

Biological Activity

Ethylene dimethanesulfonate is a mild alkylated ethylene glycol nonvolatile methanesulfonate diester. It has a selective pro-apoptotic effect on LC.

in vivo

Ethylene dimethanesulfonate (subcutaneous injection; 75 mg/kg; 7 days) disrupts epididymal function and leads to sperm granuloma formation in rat.

References

[1] Dutta D, et al. Ethylene dimethane sulfonate (EDS) ablation of Leydig cells in adult rat depletes testosterone resulting in epididymal sperm granuloma: Testosterone replacement prevents granuloma formation. Reprod Biol. 2019 Mar;19(1):89-99. DOI:10.1016/j.repbio.2018.11.005

ethylene dimethanesulfonate(4672-49-5)Related Product Information

• FENCHYL ACETATE
• Isononyl acetate
• ISO-DECYL-ACETATE
• 2-TERTIARY PENTYL CYCLOHEXANYL ACETATE
• SUCROSE ACETATE ISOBUTYRATE
• ETHYL LINALYL ACETATE
• ISO-TRIDECYL-ACETATE
• Cinnamylcetate
• SUCROSE ACETATE ISOBUTYRATE
• 1-ACETOXY-2-METHOXY-4-(1-PROPENYL)BENZENE
• TERPINYL ACETATE
• 1,2-Ethanedisulfonic acid
• Ethylenebis(oxyethylenenitrilo)tetraacetic acid
• 1,2-BIS(TOSYLOXY)ETHANE
• ethylene dimethanesulfonate
• METHYL-4,6-O-BENZYLIDENE-2,3-DI-(O-TOSYL)-A-D-GLUCOPYRANOSIDE
• (S)-(-)-1,2-PROPANEDIOL DI-P-TOSYLATE
• (S)-1,2,4-BUTANETRIOL TRIMESYLATE