2-methyl-1,3-thiazole-5-carboxylic acid Chemical Properties

Melting point:

209 °C(Solv: water (7732-18-5))

Boiling point:

301.2±15.0 °C(Predicted)

Density 

1.418±0.06 g/cm3(Predicted)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

form 

powder to crystal

pka

3.78±0.10(Predicted)

color 

White to Almost white

InChI

InChI=1S/C5H5NO2S/c1-3-6-2-4(9-3)5(7)8/h2H,1H3,(H,7,8)

InChIKey

QCXCIYPOMMIBHO-UHFFFAOYSA-N

SMILES

S1C(C(O)=O)=CN=C1C

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/39

Safety Statements 

26-37

RTECS 

XJ3678500

HS Code 

29341000

2-methyl-1,3-thiazole-5-carboxylic acid Usage And Synthesis

Synthesis

To a stirred solution of 2-methyl-thiazole-5-carboxylic acid ethyl ester (1.3 g, 8.0 mmol) in dioxane (12 mL) at room temperature was added NaOH (2N, 12 mL). After 1 h the reaction mixture was neutralized with HCl (IN, 12 mL), then filtered and the collected solid dried in vacuo to give 2-methyl-1,3-thiazole-5-carboxylic acid (758 mg, 70percent) as an off white solid.

2-methyl-1,3-thiazole-5-carboxylic acid(40004-69-1)Related Product Information

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• 5-Methyl-1,3-thiazole-2-carboxylic acid
• 4-Methyl-1,3-thiazole-2-carboxylic acid
• 4-METHYL-2-[3-(TRIFLUOROMETHYL)PHENYL]-1,3-THIAZOLE-5-CARBOXYLIC ACID
• ETHYL 4-METHYL-2-[3-(TRIFLUOROMETHYL)PHENYL]-1,3-THIAZOLE-5-CARBOXYLATE