ChemicalBook > CAS DataBase List > 2-methyl-1,3-thiazole-5-carboxylic acid

2-methyl-1,3-thiazole-5-carboxylic acid

Product Name
2-methyl-1,3-thiazole-5-carboxylic acid
CAS No.
40004-69-1
Chemical Name
2-methyl-1,3-thiazole-5-carboxylic acid
Synonyms
RU-21933;5-Carboxy-2-methyl-1,3-thiazole;2-methylthiazole-5-carboxylic acid;2-Methyl-5-thiazolecarboxylic acid;5-Thiazolecarboxylicacid, 2-Methyl-;2-Methylthiazole-5-carboxylicAcid>2-methyl-1,3-thiazole-5-carboxylic acid;2-methyl-1,3-thiazole-5-carboxylic acid(SALTDATA: FREE)
CBNumber
CB31455996
Molecular Formula
C5H5NO2S
Formula Weight
143.16
MOL File
40004-69-1.mol
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2-methyl-1,3-thiazole-5-carboxylic acid Property

Melting point:
209 °C(Solv: water (7732-18-5))
Boiling point:
301.2±15.0 °C(Predicted)
Density 
1.418±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
powder to crystal
pka
3.78±0.10(Predicted)
color 
White to Almost white
InChI
InChI=1S/C5H5NO2S/c1-3-6-2-4(9-3)5(7)8/h2H,1H3,(H,7,8)
InChIKey
QCXCIYPOMMIBHO-UHFFFAOYSA-N
SMILES
S1C(C(O)=O)=CN=C1C
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/39
Safety Statements 
26-37
RTECS 
XJ3678500
HS Code 
29341000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
M2626
Product name
2-Methylthiazole-5-carboxylic Acid
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$94
Updated
2025/07/31
TCI Chemical
Product number
M2626
Product name
2-Methylthiazole-5-carboxylic Acid
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$377
Updated
2025/07/31
Usbiological
Product number
281860
Product name
2-Methyl-1,3-thiazole-5-carboxylic acid
Packaging
2g
Price
$333
Updated
2021/12/16
TRC
Product number
B486013
Product name
2-Methyl-1,3-thiazole-5-carboxylicacid
Packaging
100mg
Price
$75
Updated
2021/12/16
Chem-Impex
Product number
44039
Product name
2-Methylthiazole-5-carboxylicacid,≥98%(GC)
Purity
≥98%(GC)
Packaging
5G
Price
$265.78
Updated
2021/12/16
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2-methyl-1,3-thiazole-5-carboxylic acid Chemical Properties,Usage,Production

Synthesis

To a stirred solution of 2-methyl-thiazole-5-carboxylic acid ethyl ester (1.3 g, 8.0 mmol) in dioxane (12 mL) at room temperature was added NaOH (2N, 12 mL). After 1 h the reaction mixture was neutralized with HCl (IN, 12 mL), then filtered and the collected solid dried in vacuo to give 2-methyl-1,3-thiazole-5-carboxylic acid (758 mg, 70percent) as an off white solid.

References

[1] Journal of the American Chemical Society, 2016, vol. 138, # 44, p. 14639 - 14649
[2] Patent: WO2010/127974, 2010, A1. Location in patent: Page/Page column 43; 44
[3] Patent: WO2018/160878, 2018, A1. Location in patent: Page/Page column 279
[4] Chemische Berichte, 1940, vol. 73, p. 1240,1252
[5] Australian Journal of Chemistry, 2004, vol. 57, # 6, p. 599 - 604

2-methyl-1,3-thiazole-5-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2-methyl-1,3-thiazole-5-carboxylic acid Suppliers

Americas 1 China 161 Europe 1 Germany 4 India 6 Japan 2 South Korea 1 United Kingdom 8 United States 24 Global 208
Suzhou Zehou Biotechnology Co. , Ltd.
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0512-68716880 19984816880
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sales@growingchem.com
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THchemica Co.,Ltd.
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0573-82835115 18969301519
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tly1019@126.com
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China
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Shanghai GaoLang Chemical Technology Co., Ltd.
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021-57340939 18017297327
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sales@gaolangchemical.com
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Milestone Chemical Wuxi Co.,Ltd
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18068271528
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1917265470@qq.com
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China
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J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
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jkinfo@jkchemical.com
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ITIC MEDCHEM(SUZHOU) CO.,LTD.
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0512-68323967 18015559028
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+86-512-69200360
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sales@iticmedchem.com
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400-021-7337 2355568890
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0086-21-50182339
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sales@demochem.com
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Energy Chemical
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021-58436166
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Shanghai Chemical Pharm-Intermediate Tech.Co., Ltd.
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21-54820552 18964669552
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086-21-64964478
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JinYan Chemicals(ShangHai) Co.,Ltd.
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13817811078
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86-021-50426522,50426273
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sales@jingyan-chemical.com
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China
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View Lastest Price from 2-methyl-1,3-thiazole-5-carboxylic acid manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
2-Methyl-5-thiazolecarboxylic acid 40004-69-1
Price
US $1.10-9.90/KG
Min. Order
1KG
Purity
99% min
Supply Ability
100kg
Release date
2025-08-18
Shaanxi Dideu Medichem Co. Ltd
Product
5-Thiazolecarboxylicacid, 2-Methyl 40004-69-1
Price
US $1.00-1.50/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000KG
Release date
2024-08-16
Milestone Chemical Wuxi Co.,Ltd
Product
2-Methyl-1,3-thiazole-5-carboxylic acid 40004-69-1
Price
US $0.00-0.00/gkg
Min. Order
1gkg
Purity
98%
Supply Ability
20tons
Release date
2023-03-20

40004-69-1, 2-methyl-1,3-thiazole-5-carboxylic acidRelated Search:

2,4-Dimethylthiazole-5-carboxylic acid ETHYL 4-METHYL-2-PHENYL-1,3-THIAZOLE-5-CARBOXYLATE 4-METHYL-2-[4-(TRIFLUOROMETHYL)PHENYL]THIAZOLE-5-CARBOXYLIC ACID 4-METHYL-2-PHENYL-THIAZOLE-5-CARBOXYLIC ACID 4-METHYL-2-(3-PYRIDINYL)-1,3-THIAZOLE-5-CARBOXYLIC ACID ETHYL 2,4-DIMETHYLTHIAZOLE-5-CARBOXYLATE Ethyl 4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxylate 2-[1-(TERT-BUTOXYCARBONYL)PIPERIDIN-4-YL]-4-METHYL-1,3-THIAZOLE-5-CARBOXYLIC ACID 4-METHYL-1,3-THIAZOLE-5-CARBOXYLIC ACID 2-BROMO-4-METHYL-1,3-THIAZOLE-5-CARBOXYLIC ACID 2-AMINO-4-METHYL-1,3-THIAZOLE-5-CARBOXYLIC ACID 2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid 2-METHYL-1,3-THIAZOLE-4-CARBOXYLIC ACID,2-Methyl-1,3-thiazole-4-carboxylic acid ,97% 2-METHYL-1,3-THIAZOLE-4-CARBOXYLIC ACID AMIDE 5-Methyl-1,3-thiazole-2-carboxylic acid 4-Methyl-1,3-thiazole-2-carboxylic acid 4-METHYL-2-[3-(TRIFLUOROMETHYL)PHENYL]-1,3-THIAZOLE-5-CARBOXYLIC ACID ETHYL 4-METHYL-2-[3-(TRIFLUOROMETHYL)PHENYL]-1,3-THIAZOLE-5-CARBOXYLATE

  • 5-Thiazolecarboxylicacid, 2-Methyl-
  • 2-Methyl-5-thiazolecarboxylic acid
  • RU-21933
  • 2-methylthiazole-5-carboxylic acid
  • 2-methyl-1,3-thiazole-5-carboxylic acid
  • 2-methyl-1,3-thiazole-5-carboxylic acid(SALTDATA: FREE)
  • 5-Carboxy-2-methyl-1,3-thiazole
  • 2-Methylthiazole-5-carboxylicAcid&gt
  • 40004-69-1
  • 40004-69-2
  • Thiazole series
  • Carboxylic Acids
  • Thiazoles, Isothiazoles &Benzothiazoles
  • Carboxylic Acids
  • Thiazoles, Isothiazoles & Benzothiazoles