3-(2-hydroxyethoxy)propanoic acid Chemical Properties

Boiling point:

127-130 °C(Press: 2 Torr)

Density 

1.224±0.06 g/cm3(Predicted)

storage temp. 

Storage temp. 2-8°C

form 

Liquid

pka

4.26±0.10(Predicted)

color 

Colorless to light yellow

3-(2-hydroxyethoxy)propanoic acid Usage And Synthesis

Uses

Hydroxy-PEG1-acid is a non-cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC 50

Non-cleavable Linker

References

[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268

3-(2-hydroxyethoxy)propanoic acid(89211-34-7)Related Product Information

• Bromo-PEG1-Acid
• Br-PEG5-CH2COOH
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