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3-Hydroxypropionic acid

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3-Hydroxypropionic acid Basic information

Product Name:
3-Hydroxypropionic acid
Synonyms:
  • .beta.-Hydroxypropionicacid
  • .beta.-Lacticacid
  • beta-lacticacid
  • ethylenelacticacid
  • Glycericacid,2-deoxy-
  • Hydracrylic-acid-ethylenelacticacid
  • Propionicacid,3-hydroxy-
  • β-Hydroxypropionsαure
CAS:
503-66-2
MF:
C3H6O3
MW:
90.08
EINECS:
207-974-8
Product Categories:
  • omega-Functional Alkanols, Carboxylic Acids, Amines & Halides
  • omega-Hydroxycarboxylic Acids
  • Aliphatics
  • Carboxylic Acids
  • Carboxylic Acids
Mol File:
503-66-2.mol
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3-Hydroxypropionic acid Chemical Properties

Melting point:
16.8°C (estimate)
Boiling point:
212°C (rough estimate)
Density 
1.066 g/mL at 25 °C
refractive index 
1.4489
storage temp. 
2-8°C
solubility 
Ethanol, Methanol, Water
pka
4.51(at 25℃)
form 
Colourless Solution
color 
Colorless to Almost colorless
Water Solubility 
270.1g/L(25 ºC)
InChI
InChI=1S/C3H6O3/c4-2-1-3(5)6/h4H,1-2H2,(H,5,6)
InChIKey
ALRHLSYJTWAHJZ-UHFFFAOYSA-N
SMILES
C(O)(=O)CCO
CAS DataBase Reference
503-66-2(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-41-37/38-22
Safety Statements 
26-36/37/39-39
HS Code 
29181990
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3-Hydroxypropionic acid Usage And Synthesis

Description

3-Hydroxypropionic acid (3-HP) is considered as a potential building block either for organic synthesis or high performance polymers.It is a 3-carbon carboxylic acid, structural isomer of lactic acid, which naturally exists in some thermophilic archaea and bacteria. This organic compound has been pointed out by the US Department of Energy as a promising biomass derivate, which could potentially be used for the production of high added-value chemicals like1,3-propanediol, acrylic acid, acrylamide, and bioplastics.
Being 3-HP a commercially valuable, important platform chemical, researches have been conducted about its production on commercial scale, mainly from renewable sources. The biological production of 3-HP from glycerol and glucose, both based on microbial fermentation, are among the main routes studied. More specifically, research activities have been devoted to goals such as identifying novel biochemical pathways, metabolic engineering of microbial strains for the production of 3-HP, and improvements of cultivation techniques to increase 3-HP production titers.
Despite intense research efforts, there are still important bottlenecks for cost efficient, large scale biological production of 3-Hydroxypropionic Acid.

Uses

3-Hydroxypropionic Acid induces gene expressions and also functions as a reagent for industrial application.

Uses

A three carbon non-chiral compound, 3-Hydroxypropionic acid can be used as a building block for industrial chemicals.

Definition

ChEBI: A 3-hydroxy monocarboxylic acid that is propionic acid in which one of the hydrogens attached to the terminal carbon is replaced by a hydroxy group.

Production Methods

β-Hydroxypropionic acid can be prepared by alkaline hydration of acrylic acid or by treatment of ethylene chlorohydrin with sodium cyanide, followed by hydrolysis of the resulting β-hydroxypropionitrile. It is also readily obtained by hydrolysis of the commercially important and easily accessible compound β-propiolactone.

3-Hydroxypropionic acid Preparation Products And Raw materials

Preparation Products

Raw materials

3-Hydroxypropionic acidSupplier

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