Basic information Safety Supplier Related

(+/-)12-HETE

Basic information Safety Supplier Related

(+/-)12-HETE Basic information

Product Name:
(+/-)12-HETE
Synonyms:
  • (+/-)12-HYDROXYEICOSA-5Z,8Z,10E,14Z-TETRAENOIC ACID
  • (+/-)12-HYDROXY-5Z,8Z,10E,14Z-EICOSATETRAENOIC ACID
  • (+/-)12-HETE
  • 10,14-eicosatetraenoicacid,12-hydroxy-,(e,z,z,z)-8
  • 12-hydroxyeicosatetraenoicacid
  • (5E,8Z,10Z,14Z)-12-hydroxyicosa-5,8,10,14-tetraenoic acid
  • (5Z,8Z,10E,14Z)-12-Hydroxy-5,8,10,14-icosatetraenoic acid
  • (5Z,8Z,10E,14Z)-12-Hydroxyicosa-5,8,10,14-tetraenoic acid
CAS:
71030-37-0
MF:
C20H32O3
MW:
320.47
Mol File:
71030-37-0.mol
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(+/-)12-HETE Chemical Properties

Boiling point:
487.7±45.0 °C(Predicted)
Density 
0.984±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS (pH 7.2): 0.8 mg/ml
pka
4.75±0.10(Predicted)
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(+/-)12-HETE Usage And Synthesis

Description

(±)12-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. The biological activity of (±)12-HETE is similar to that of its constituent enantiomers (Item Nos. 34560 and 34570). It aggregates neutrophils with an EC50 value of 40 nM.

Definition

ChEBI: (5Z,8Z,10E,14Z)-12-hydroxyicosatetraenoic acid is the (5Z,8Z,10E,14Z)-stereoisomer of 12-HETE. It has a role as a mouse metabolite. It is a conjugate acid of a 12-HETE(1-).

(+/-)12-HETESupplier

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