IRL-1038
IRL-1038 Basic information
- Product Name:
- IRL-1038
- Synonyms:
-
- IRL-1038
- IRL-1038, HUMAN
- H-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH
- [CYS11-CYS15]-ENDOTHELIN-1 (11-21)
- Endothelin-1 (11-21) trifluoroacetate salt
- [CYS11, CYS15]ENDOTHELIN-I (11-21)
- CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP
- ENDOTHELIN-1 (11-21)
- CAS:
- 144602-02-8
- MF:
- C68H92N14O15S2
- MW:
- 1409.67
- Product Categories:
-
- Endothelin receptor
- Mol File:
- 144602-02-8.mol
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IRL-1038 Chemical Properties
- storage temp.
- -15°C
- solubility
- Soluble to 1 mg/ml in 20% acetonitrile
- form
- Solid
- Sensitive
- Light Sensitive
- Sequence
- Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp (Disulfide bridge:Cys1-Cys5)
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IRL-1038 Usage And Synthesis
Uses
IRL 1038 is an endothelin B receptor selective antagonist with a Ki of 6-11 nM[1].
References
[1] Urade Y, et al. An endothelin B receptor-selective antagonist: IRL 1038, [Cys11-Cys15]-endothelin-1(11-21). FEBS Lett. 1992 Oct 12;311(1):12-6. doi: 10.1016/0014-5793(92)81355-p. DOI:10.1016/0014-5793(92)81355-p
IRL-1038Supplier
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