Propynol ethoxylate Chemical Properties

Boiling point:

80-90 °C(Press: 12-14 Torr)

Density 

1.0261

refractive index 

1.4502

storage temp. 

Sealed in dry,Store in freezer, under -20°C

solubility 

Chloroform (Sparingly), Ethyl Acetate (Slightly)

form 

Oil

pka

14.22±0.10(Predicted)

color 

Colourless to Pale Yellow

Stability:

Light Sensitive

InChI

InChI=1S/C5H8O2/c1-2-4-7-5-3-6/h1,6H,3-5H2

InChIKey

GHGCQQRMJCSIBQ-UHFFFAOYSA-N

SMILES

C(O)COCC#C

CAS DataBase Reference

3973-18-0(CAS DataBase Reference)

EPA Substance Registry System

Ethanol, 2-(2-propynyloxy)- (3973-18-0)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36

Safety Statements 

26

HS Code 

2909498090

Propynol ethoxylate Usage And Synthesis

Description

Propargyl-PEG2-alcohol has propargyl and alcohol end groups. The propargyl can participate in copper-catalyzed Click Chemistry reactions with azides.

Chemical Properties

Propynol ethoxylate(PME) is a clear colourless to pale yellow oil.

Uses

Propynol Ethoxylate is an intermediate and it is shown to be used in the design and synthesis of a tag-free chemical probe for photoafiinity labeling.

Application

Propynol ethoxylate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Propynol Ethoxylate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

General Description

Propynol ethoxylate, known as 2-propyn-1-ol, is a colourless flammable liquid with a pleasant odour. This volatile organic compound (VOC) occurs naturally in plants and animals and can also be synthesised in a laboratory environment. Propargyl alcohol polyoxyethylene ether has a wide range of applications and plays an important role in scientific research and industrial processes. It is used as a fuel, solvent and reagent in chemical reactions, as well as an important ingredient in the manufacture of many pharmaceuticals and industrial products. In scientific research, it is used as a reagent in organic synthesis, as a solvent in analytical chemistry and as a fuel in combustion studies.

Propynol ethoxylate(3973-18-0)Related Product Information

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