2,3-Pyrazinecarboxylic anhydride Chemical Properties

Melting point:

210 °C (dec.)(lit.)

Boiling point:

357.3±22.0 °C(Predicted)

Density 

1.686±0.06 g/cm3(Predicted)

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Actonitrile (Slightly), DMSO

form 

Solid

pka

-3.43±0.20(Predicted)

color 

White to light brown crystalline powder

LogP

-0.900 (est)

CAS DataBase Reference

4744-50-7(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

Hazard Note 

Irritant

HS Code 

29349990

MSDS

• Language:English Provider:SigmaAldrich

2,3-Pyrazinecarboxylic anhydride Usage And Synthesis

Uses

2,?3-?Pyrazinedicarboxylic Anhydride is a reagent used in the synthesis of highly potent and selective abietane type diterpenoid amides.

Synthesis

Pyrazine-2,3-dicarboxylic acid (4.0 g, 23.8 mmol) was dissolved in acetic anhydride (30 mL).The reaction mixture was refluxed for one hour, and subsequently cooled down to 0 °C in ice bath.The obtained crystals of pyrazine-2,3-dicarboxylic anhydride were filtered off (yield 70%).

2,3-Pyrazinecarboxylic anhydride(4744-50-7)Related Product Information

• RP 48497 (Eszopiclone Impurity C)
• 1-Piperazinecarboxylicacid,4-methyl-,ethylester(6CI,9CI)
• 2,3-Pyrazinedicarboxylic acid
• Trifluoromethanesulfonic anhydride
• Pyrazinamide
• Pyrazine
• Sulfachoropyrazine sodium
• Glipizide
• Isatoic Anhydride
• CIS-BUTENEDIOIC ANHYDRIDE
• Phthalic anhydride
• Zopiclone Impurity 10
• ZOPICLONE N-OXIDE
• Zopiclone Impurity 18
• Zopiclone Impurity 3
• N-(5-Chloro-2-pyridinyl)-3-(hydroxyMethyl)-2-pyrazinecarboxaMide
• Deschloro-Zopiclone
• N,N'-Dimethylpiperazine