ZOPICLONE N-OXIDE Chemical Properties

Melting point:

>140°C (dec.)

Flash point:

9℃

storage temp. 

2-8°C

solubility 

Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)

pka

4.92±0.20(Predicted)

color 

White to Light Brown

Safety Information

Hazard Codes 

F,T

Risk Statements 

11-23/24/25-39/23/24/25

Safety Statements 

7-16-36/37-45

RIDADR 

UN1230 - class 3 - PG 2 - Methanol

WGK Germany 

1

HS Code 

2933790002

ZOPICLONE N-OXIDE Usage And Synthesis

Chemical Properties

Off-White to Pale Beige Solid

Uses

A metabolite of Zopiclone

Uses

Eszopiclone impurity A.

General Description

Zopiclone N-oxide is a primary, active metabolite of zopiclone in urine as well as a major pharmaceutical impurity of zopiclone known as eszopiclone impurity A. The parent drug, zopiclone, is a non-benzodiazepine hypnotic sold under the trade names Imovane^?and ZImovane^?and is used in the treatment of insomnia.

ZOPICLONE N-OXIDE(43200-96-0)Related Product Information

• 6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl piperazine-1-carboxylate hydrochloride
• 6-(5-Chloro-2-pyridyl)-6,7-dihydro-7-hydroxy-5H-pyrrolo[3,4-b]pyrazin-5-one
• Eszopiclone
• Levetiracetam impurity 1
• N-(5-Chloro-2-pyridinyl)-2-pyrazinecarboxaMide (Zopiclone IMpurity)
• 2-Amino-5-chloropyridine
• Zopiclone
• RP 48497 (Eszopiclone Impurity C)
• N-(5-Chloro-2-pyridinyl)-3-(hydroxyMethyl)-2-pyrazinecarboxaMide
• ZOPICLONE OXIDE
• Zopiclone iMpurity (5-(Chloropyridine-2-yl-carbaMoyl)pyrazine)
• Zopiclone iMpurity A
• N-Boc-N-desmethyl Zopiclone
• 1-Piperazinecarboxylicacid,4-methyl-,ethylester(6CI,9CI)
• Zopiclone Impurity 10
• Zopiclone Impurity 18
• Zopiclone Impurity 3
• Deschloro-Zopiclone