Basic information Safety Supplier Related

(1R,5S)-5-(Dimethylphenylsilyl)-2-(hydroxymethyl)-2-cyclopentene-1-carboxylic acid

Basic information Safety Supplier Related

(1R,5S)-5-(Dimethylphenylsilyl)-2-(hydroxymethyl)-2-cyclopentene-1-carboxylic acid Basic information

Product Name:
(1R,5S)-5-(Dimethylphenylsilyl)-2-(hydroxymethyl)-2-cyclopentene-1-carboxylic acid
Synonyms:
  • (1R,5S)-5-(Dimethylphenylsilyl)-2-(hydroxymethyl)-2-cyclopentene-1-carboxylic acid
  • (5S)-5-(dimethyl(phenyl)silyl)-2-(hydroxymethyl)cyclopent-2-enecarboxylic acid
  • 2-Cyclopentene-1-carboxylic acid,5-(dimethylphenylsilyl)-2-(hydroxymethyl)-,(1R,5S)-
  • (1R,5S)-5-(dimethyl(phenyl)silyl)-2-(hydroxymethyl)cyclopent-2-ene-1-carboxylicacid
  • EOS-61484
  • (5S)-5-(dimethyl(phenyl)silyl)-2-(hydroxymethyl)cyclopent-2-ene-1-carboxylic acid
  • 5-[dimethyl(phenyl)silyl]-2-(hydroxymethyl)-1-cyclopent-2-enecarboxylic acid
CAS:
649761-21-7
MF:
C15H20O3Si
MW:
276.4
EINECS:
1806241-263-5
Mol File:
649761-21-7.mol
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(1R,5S)-5-(Dimethylphenylsilyl)-2-(hydroxymethyl)-2-cyclopentene-1-carboxylic acid Chemical Properties

Boiling point:
433.3±45.0 °C(Predicted)
Density 
1.14
pka
4.50±0.60(Predicted)
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(1R,5S)-5-(Dimethylphenylsilyl)-2-(hydroxymethyl)-2-cyclopentene-1-carboxylic acid Usage And Synthesis

Uses

(1R,5S)-5-?(Dimethylphenylsilyl?)?-?2-?(hydroxymethyl)?-2-?cyclopentene-?1-?carboxylic Acid is the intermediate of Entecavir (E558900), which is used in the treatment of hepatitis B infection. A guanine analogue that inhibits all three steps in the viral replication process.

(1R,5S)-5-(Dimethylphenylsilyl)-2-(hydroxymethyl)-2-cyclopentene-1-carboxylic acidSupplier

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